Critical concentrations of cadmium in human renal cortex: dose-effect studies in cadmium smelter workers

Journal Article · Fri May 01 04:00:00 EDT 1981 · J. Toxicol. Environ. Health; (United States)

DOI:https://doi.org/10.1080/15287398109530012· OSTI ID:6194245

Ellis, K J ^[1]; Morgan, W D; Zanzi, I; Yasumura, S; Vartsky, D; Cohn, S H

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1. Brookhaven National Lab., NY

Cadmium was measured in vivo in the left kidney and liver of 82 industrially exposed workers and 10 control subjects. The range of Cd values for the industrial group was 0.9 to 57 mg for the whole kidney and 0.8 to 120 ppM for the liver, compared to 0.4 to 11.8 mg and 0.6 to 7.9 ppM for the control group. Below 40 ppM in the liver, the kidney Cd burden tended to increase with increasing liver concentration. Above 40 ppM, the kidney Cd content decreased as the liver concentration increased. The biphasic relation between Cd in the kidney and the liver for all subjects showed a critical level of approximately 31 mg Cd in the kidney.

• OSTI ID: 6194245
• Journal Information: J. Toxicol. Environ. Health; (United States), Journal Name: J. Toxicol. Environ. Health; (United States) Vol. 7:5; ISSN JTEHD
• Country of Publication: United States
• Language: English

Related Subjects

560306* -- Chemicals Metabolism & Toxicology-- Man-- (-1987)
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ACTIVATION ANALYSIS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BODY
CADMIUM
CADMIUM 113
CADMIUM ISOTOPES
CHEMICAL ANALYSIS
CHRONIC EXPOSURE
DIGESTIVE SYSTEM
DOSE-RESPONSE RELATIONSHIPS
ELEMENTS
EVEN-ODD NUCLEI
GLANDS
INTERMEDIATE MASS NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
KIDNEYS
LIVER
METALS
NUCLEI
ORGANS
PERSONNEL
RADIOISOTOPES
SMELTING
STABLE ISOTOPES
YEARS LIVING RADIOISOTOPES