Quadruople ion trap instrumentation for the study of multiply-charged ion reactions
Conference
·
OSTI ID:61888
- Oak Ridge National Lab., TN (United States)
The authors have adapted an electrospray/ion trap combination to allow for a heated vacuum system. By increasing the temperature and the average collisional energy the authors are studying changes in the dissociation behavior of multiply-charged ions as a function of internal energy. This set-up has allowed trapping and storage (1 second) of multiply-charged skeletal muscle horse heart myoglobin molecules and to monitor the loss of the Heme group from the native state protein as a function of bath gas temperature. The authors have demonstrated that gas phase trapped ions may be thermally activated at temperatures which are amenable to commercial quadrupole ion traps. The thermal activation and collisional activation products are indistinguishable. Current efforts are directed towards correlating the effects of bath gas temperature with the resonant excitation threshold measurements for collisional activation.
- DOE Contract Number:
- AC05-84OR21400
- OSTI ID:
- 61888
- Report Number(s):
- CONF-9405234--
- Country of Publication:
- United States
- Language:
- English
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