Radiotherapy of early glottic cancer. II. [Results and complications of /sup 60/co therapy]

Journal Article · Sun Apr 01 04:00:00 EST 1979 · Int. J. Radiat. Oncol., Biol. Phys.; (United States)

DOI:https://doi.org/10.1016/0360-3016(79)90809-5· OSTI ID:6146402

Harwood, A R

A detailed retrospective analysis of the results and complications of treatment of early glottic cancers is presented. Two hundred and four patients treated by radiotherapy at the Antoni van Leeuwenhoek Ziekenhuis in Amsterdam are reviewed. The results are analyzed in terms of local control, cure and complication rates. These data are compared and contrasted with a similar group of patients treated at the Princess Margaret Hospital during the same time period. It is concluded that the risk of major complications in the larynx from radiotherapy rises very rapidly once the dose of 2050 ret is exceeded. The presence of diabetes and/or hypertension and the severity of acute reaction are related to the subsequent risk of major complications. The dose cure curve for early glottic cancer has been found to be flat over the dose range considered (1650 to 2050 ret).

• Research Organization: Princess Margaret Hospital, Toronto, Ontario
• OSTI ID: 6146402
• Journal Information: Int. J. Radiat. Oncol., Biol. Phys.; (United States), Journal Name: Int. J. Radiat. Oncol., Biol. Phys.; (United States) Vol. 5:4; ISSN IOBPD
• Country of Publication: United States
• Language: English

Related Subjects

550603 -- Medicine-- External Radiation in Therapy-- (1980-)
560151* -- Radiation Effects on Animals-- Man
62 RADIOLOGY AND NUCLEAR MEDICINE
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
BODY
BODY AREAS
CARCINOMAS
CARDIOVASCULAR DISEASES
COBALT 60
COBALT ISOTOPES
DATA
DATA FORMS
DELAYED RADIATION EFFECTS
DIABETES MELLITUS
DISEASES
EARLY RADIATION EFFECTS
EDEMA
ELECTROMAGNETIC RADIATION
ENDOCRINE DISEASES
EXPERIMENTAL DATA
EXTERNAL IRRADIATION
FRACTIONATED IRRADIATION
GAMMA RADIATION
HYPERTENSION
INFLAMMATION
INFORMATION
INTERMEDIATE MASS NUCLEI
INTERNAL CONVERSION RADIOISOTOPES
IONIZING RADIATIONS
IRRADIATION
ISOLATED VALUES
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
LARYNX
LOCAL IRRADIATION
LUNGS
MALFORMATIONS
MEDICINE
MINUTES LIVING RADIOISOTOPES
MUSCLES
NECK
NECROSIS
NEOPLASMS
NUCLEAR MEDICINE
NUCLEI
NUMERICAL DATA
ODD-ODD NUCLEI
ORGANS
PATHOLOGICAL CHANGES
PATIENTS
PNEUMONIA
RADIATION EFFECTS
RADIATIONS
RADIOINDUCTION
RADIOISOTOPES
RADIOLOGY
RADIOSENSITIVITY EFFECTS
RADIOTHERAPY
RESPIRATORY SYSTEM
RESPIRATORY SYSTEM DISEASES
RISK ASSESSMENT
SIDE EFFECTS
SYMPTOMS
THERAPY
VASCULAR DISEASES
YEARS LIVING RADIOISOTOPES