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Resolution of the African hominoid trichotomy by use of a mitochondrial gene sequence

Journal Article · · Proceedings of the National Academy of Sciences of the United States of America; (United States)
; ;  [1];  [2];  [3]
  1. Harvard Univ., Cambridge, MA (United States)
  2. Univ. of Michigan, Ann Arbor (United States)
  3. Texas A and M Univ., College Station (United States)
+ Show Author Affiliations

Mitochondrial DNA sequences encoding the cytochrome oxidase subunit II gene have been determined for five primate species, siamang (Hylobates syndactylus), lowland gorilla (Gorilla gorilla), pygmy chimpanzee (Pan paniscus), crab-eating macaque (Macaca fascicularis), and green monkey (Cercopithecus aethiops), and compared with published sequences of other primate and nonprimate species. Comparisons of cytochrome oxidase subunit II gene sequences provide clear-cut evidence from the mitochondrial genome for the separation of the African ape trichotomy into two evolutionary lineages, one leading to gorillas and the other to humans and chimpanzees. Several different tree-building methods support this same phylogenetic tree topology. The comparisons also yield trees in which a substantial length separates the divergence point of gorillas from that of humans and chimpanzees, suggesting that the lineage most immediately ancestral to humans and chimpanzees may have been in existence for a relatively long time.

OSTI ID:
6144375
Journal Information:
Proceedings of the National Academy of Sciences of the United States of America; (United States), Journal Name: Proceedings of the National Academy of Sciences of the United States of America; (United States) Vol. 88:4; ISSN PNASA; ISSN 0027-8424
Country of Publication:
United States
Language:
English

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Related Subjects

550401* -- Genetics-- Tracer Techniques
59 BASIC BIOLOGICAL SCIENCES
ANIMALS
APES
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BIOLOGICAL EVOLUTION
CELL CONSTITUENTS
CYTOCHROME OXIDASE
DAYS LIVING RADIOISOTOPES
DNA SEQUENCING
ENZYMES
EVEN-ODD NUCLEI
GENE AMPLIFICATION
GENES
HAEM DEHYDROGENASES
ISOTOPES
LIGHT NUCLEI
MAMMALS
MITOCHONDRIA
NUCLEI
OXIDOREDUCTASES
PRIMATES
RADIOISOTOPES
STRUCTURAL CHEMICAL ANALYSIS
SULFUR 35
SULFUR ISOTOPES
VERTEBRATES