Gastric emptying measurements: delayed and complex emptying patterns without appropriate correction

Journal Article · Tue Oct 01 04:00:00 EDT 1985 · J. Nucl. Med.; (United States)

OSTI ID:6084746

Moore, J G; Christian, P E; Taylor, A T; Alazraki, N

Anteriorly acquired and geometric mean corrected gastric emptying curves of solids and liquid isotopic-labeled meals were compared in 37 subjects given 61 meals of three different sizes. Anterior data alone consistently and significantly underestimated solid-phase gastric emptying rates with all meal sizes when compared to geometric mean acquired data. However, with liquids there were only slight differences between anterior and anterior and posterior geometric mean corrected emptying-rates. The difference probably reflects greater attenuation of the 140 kev photon of /sup 99m/Tc compared to the 247 keV photon of In. With anterior data alone, an apparent early delay in emptying of solids was present with all meal sizes and the resultant emptying curves were nonlinear in shape. Geometric mean correction resulted in the linearization of the solid-phase emptying curves and essentially eliminated the apparent delay in emptying or lag phase noted with the anterior data alone. Based on our results, geometric mean correction techniques are necessary for accurate assessment of radioisotopic-labeled solid meals.

• Research Organization: Veterans Administration Medical Center, Salt Lake City, UT
• OSTI ID: 6084746
• Journal Information: J. Nucl. Med.; (United States), Journal Name: J. Nucl. Med.; (United States) Vol. 10; ISSN JNMEA
• Country of Publication: United States
• Language: English

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62 RADIOLOGY AND NUCLEAR MEDICINE
AMINO ACIDS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BEVERAGES
BODY
CARBOXYLIC ACIDS
CHELATING AGENTS
COLLOIDS
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DIGESTION
DIGESTIVE SYSTEM
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DRUGS
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ELECTRON CAPTURE RADIOISOTOPES
FOOD
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INDIUM 111
INDIUM ISOTOPES
INTERMEDIATE MASS NUCLEI
ISOMERIC NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
MINUTES LIVING RADIOISOTOPES
NUCLEI
ODD-EVEN NUCLEI
ORGANIC ACIDS
ORGANIC COMPOUNDS
ORGANS
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RADIOPROTECTIVE SUBSTANCES
RETENTION FUNCTIONS
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TECHNETIUM 99
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YEARS LIVING RADIOISOTOPES