Gastric emptying of a physiologic mixed solid-liquid meal

Journal Article · Sat May 01 00:00:00 EDT 1982 · Clin. Nucl. Med.; (United States)

DOI:https://doi.org/10.1097/00003072-198205000-00005· OSTI ID:6725971

Fisher, R S; Malmud, L S; Bandini, P; Rock, E

The purposes of this study were to use a noninvasive scintigraphic technique to measure gastric emptying of liquids and solids simultaneously, to study the interactions between emptying of the liquid and solid components of meals in normal subjects, and to employ dual isotope gastric scintigraphy to evaluate gastric emptying of liquids and solids in patients with clinical evidence of gastric outlet obstruction. The solid component of the test meal consisted of chicken liver, labeled in vivo with /sup 99m/Tc sulfur colloid, and the liquid component was water mixed with /sup 111/In DTPA. The rates of emptying were quantitated using a gamma camera on line to a digital computer. Twenty normal subjects were studied using this combined solid-liquid meal. Ten of them also ingested a liquid meal alone and ten a solid meal alone. Liquid emptied from the stomach significantly more rapidly than did solids. The emptying curve for liquids was exponential compared to a linear emptying curve for solids. The gastric emptying rate of the liquid component was slowed significantly by simultaneous ingestion of solids, but the emptying rate of solids was not affected by liquids. Several patients with clinical gastric outlet obstruction were evaluated. Both combined and selective abnormalities for gastric emptying of liquids and solids were demonstrated.

• Research Organization: Department of Medicine, Temple University School of Medicine, Philadelphia, Pennsylvania
• OSTI ID: 6725971
• Journal Information: Clin. Nucl. Med.; (United States), Vol. 7:5
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
59 BASIC BIOLOGICAL SCIENCES
INDIUM 111
ISOTOPE APPLICATIONS
STOMACH
SCINTISCANNING
TECHNETIUM 99
COMPARATIVE EVALUATIONS
DIET
DIGESTION
GASTRIC ACID
ISOMERIC NUCLEI
LABELLED COMPOUNDS
LIVER
PATIENTS
PHYSIOLOGY
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BIOLOGICAL MATERIALS
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DAYS LIVING RADIOISOTOPES
DIAGNOSTIC TECHNIQUES
DIGESTIVE SYSTEM
ELECTRON CAPTURE RADIOISOTOPES
GASTROINTESTINAL TRACT
GLANDS
HOURS LIVING RADIOISOTOPES
INDIUM ISOTOPES
INTERMEDIATE MASS NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
MATERIALS
MINUTES LIVING RADIOISOTOPES
NUCLEI
ODD-EVEN NUCLEI
ORGANS
RADIOISOTOPE SCANNING
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TECHNETIUM ISOTOPES
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