Specimen histology after one or two preoperative CF-252 implants for bulky stage IB cervical cancer
Journal Article
·
· Int. J. Radiat. Oncol., Biol. Phys.; (United States)
Using hysterectomy specimens obtained 1 month after Cf-252 neutron brachytherapy plus fractionated radiotherapy, we determined the fraction of positive and negative specimens with neutron dose for bulky Stage IB cervical cancers. The specimens obtained and studied after an initial Cf-252 insertion when the sources were newer and less decayed were more frequently negative for histological evidence of cancer than after the sources had decayed and 2 insertions were needed. After two insertions to deliver a therapeutic dose preoperatively the specimens were more frequently positive. When a larger initial dose was delivered to the tumor a larger proportion of negative specimens was noted. The size of neutron dose fraction was important to local tumor clearance and to rendering the specimens negative as well as schedule in use.
- Research Organization:
- Univ. of Kentucky Medical Center, Lexington
- OSTI ID:
- 6073080
- Journal Information:
- Int. J. Radiat. Oncol., Biol. Phys.; (United States), Journal Name: Int. J. Radiat. Oncol., Biol. Phys.; (United States) Vol. 13:10; ISSN IOBPD
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
550603* -- Medicine-- External Radiation in Therapy-- (1980-)
62 RADIOLOGY AND NUCLEAR MEDICINE
ACTINIDE ISOTOPES
ACTINIDE NUCLEI
ALPHA DECAY RADIOISOTOPES
BARYONS
BODY
CALIFORNIUM 252
CALIFORNIUM ISOTOPES
DISEASES
ELEMENTARY PARTICLES
EVEN-EVEN NUCLEI
FEMALE GENITALS
FERMIONS
HADRONS
HEAVY NUCLEI
IMPLANTS
ISOTOPES
MEDICINE
NEOPLASMS
NEUTRONS
NUCLEAR MEDICINE
NUCLEI
NUCLEONS
ORGANS
RADIATION SOURCE IMPLANTS
RADIATION SOURCES
RADIOISOTOPES
RADIOLOGY
RADIOTHERAPY
THERAPY
UTERUS
YEARS LIVING RADIOISOTOPES
62 RADIOLOGY AND NUCLEAR MEDICINE
ACTINIDE ISOTOPES
ACTINIDE NUCLEI
ALPHA DECAY RADIOISOTOPES
BARYONS
BODY
CALIFORNIUM 252
CALIFORNIUM ISOTOPES
DISEASES
ELEMENTARY PARTICLES
EVEN-EVEN NUCLEI
FEMALE GENITALS
FERMIONS
HADRONS
HEAVY NUCLEI
IMPLANTS
ISOTOPES
MEDICINE
NEOPLASMS
NEUTRONS
NUCLEAR MEDICINE
NUCLEI
NUCLEONS
ORGANS
RADIATION SOURCE IMPLANTS
RADIATION SOURCES
RADIOISOTOPES
RADIOLOGY
RADIOTHERAPY
THERAPY
UTERUS
YEARS LIVING RADIOISOTOPES