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Bioavailability of copper bound to dietary fiber in mice and rats

Journal Article · · J. Food Sci.; (United States)

The bioavailability of copper (Cu) was compared in mice or rats fed diets containing wheat bran-bound Cu and adequate Cu (unbound) or deficient Cu with cellulose or wheat bran. Cardiac and hepatic Cu content were comparable in mice fed bran-bound or adequate Cu and greater than mice fed deficient Cu. Cardiac Cu content was comparable in rats fed bran-bound Cu and adequate Cu and greater than rats fed deficient Cu. Hepatic Cu content, however, was less in rats fed bran-bound Cu than adequate Cu and greater in both than deficient Cu. Both rats and mice utilized dietary Cu bound to wheat bran, suggesting that mineral-fiber interactions may not decrease bioavailability when dietary mineral is adequate. Tissue Cu content in Cu-deficiency was lower in animals fed wheat bran compared to cellulose, suggesting that the type of fiber may exacerbate effects of mineral deficiency.

Research Organization:
Univ. of Arizona, Tucson
OSTI ID:
6062006
Journal Information:
J. Food Sci.; (United States), Journal Name: J. Food Sci.; (United States) Vol. 52:5; ISSN JFDSA
Country of Publication:
United States
Language:
English