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Autopsy study of small cardiac scars in Japanese men who lived in Hiroshima, Japan and Honolulu, Hawaii (in Japanese and English)

Technical Report ·
OSTI ID:6056960
; ; ; ; ;
Japanese men long resident in Honolulu, Hawaii have significantly more ischemic heart disease, but significantly fewer small cardiac scars than men in Hiroshima, Japan. These scars occur in three forms: (1) small scars in the mural myocardium which account for the difference in frequency of small lesions in the two cities, and are of uncertain etiology; (2) areas of diffuse fibrosis in the papillary muscles. These are equally frequent in the two cities, and are associated with advancing age and sclerosis of papillary muscle arteries; and (3) focal scars in the papillary muscles. These are more frequent in Honolulu than Hiroshima. They are healed infarcts due to ischemic heart disease and are associated with a severe degree of extramural coronary artery sclerosis. Small mural myocardial scars, when present, are usually found in multiple sites, and are not related to age at death or heart weight. They are more common in the presence of sclerosis of intramural small arteries, but this association does not explain their more frequent occurrence in Hiroshima. There is no evidence that they are related to A-bomb radiation exposure.
Research Organization:
Radiation Effects Research Foundation, Hiroshima (Japan); Radiation Effects Research Foundation, Nagasaki (Japan). Nagasaki Branch
OSTI ID:
6056960
Report Number(s):
RERF-TR-7-78
Country of Publication:
United States
Language:
Japanese and English

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Related Subjects

550100 -- Behavioral Biology
550600* -- Medicine
59 BASIC BIOLOGICAL SCIENCES
62 RADIOLOGY AND NUCLEAR MEDICINE
A-BOMB SURVIVORS
ANEMIAS
ANIMALS
ARTERIOSCLEROSIS
ASIA
AUTOPSY
BODY
CARDIOVASCULAR DISEASES
CARDIOVASCULAR SYSTEM
COMPARATIVE EVALUATIONS
DATA
DATA FORMS
DIAGNOSTIC TECHNIQUES
DISEASES
EXPERIMENTAL DATA
FIBROSIS
GEOGRAPHICAL VARIATIONS
HAWAII
HEART
HEMIC DISEASES
HIROSHIMA
INFORMATION
ISCHEMIA
ISOLATED VALUES
JAPAN
MALES
MAMMALS
MAN
MEN
MUSCLES
MYOCARDIAL INFARCTION
MYOCARDIUM
NORTH AMERICA
NUMERICAL DATA
ORGANS
PATHOLOGICAL CHANGES
PRIMATES
SYMPTOMS
USA
VARIATIONS
VERTEBRATES
WESTERN REGION