Autopsy study of cerebrovascular disease in Japanese men who lived in Hiroshima, Japan and Honolulu, Hawaii (in Japanese and English)
Evidence of cerebrovascular disease at autopsy was compared in two groups of men, 186 long time residents of Hiroshima, Japan and 253 men of Japanese ancestry long resident in Honolulu, hawaii. They were from 45 to 71 years of age at death. Atherosclerosis of the circle of Willis and its major branches, sclerosis of the intraparenchymal arteries and the frequency of cerebral hemorrhage and cerebral infarct were compared in the two populations. The Honolulu subjects had significantly more atherosclerosis of the circle of Willis, but less intraparenchymal artery sclerosis and less cerebral infarction. Cerebral hemorrhage was equally frequent in the two cities. It was concluded that cerebral infarction is more frequent in Japanese men in Hiroshima than Honolulu, and that men of Japanese ancestry in Honolulu are spared an appreciable risk of cerebral infarction through decreased frequenncy of intraparenchymal arterial sclerosis despite higher levels of atherosclerosis of large intracranial arteries.
- Research Organization:
- Radiation Effects Research Foundation, Hiroshima (Japan)
- OSTI ID:
- 6056006
- Report Number(s):
- RERF-TR-6-78
- Country of Publication:
- United States
- Language:
- Japanese and English
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59 BASIC BIOLOGICAL SCIENCES
62 RADIOLOGY AND NUCLEAR MEDICINE
ANIMALS
ASIA
AUTOPSY
BODY
BRAIN
CENTRAL NERVOUS SYSTEM
CEREBRUM
COMPARATIVE EVALUATIONS
DATA
DATA COMPILATION
DATA FORMS
DIAGNOSTIC TECHNIQUES
DISEASES
HAWAII
INFORMATION
ISOLATED VALUES
JAPAN
MALES
MAMMALS
MAN
MEN
NERVOUS SYSTEM
NORTH AMERICA
NUMERICAL DATA
ORGANS
PRIMATES
USA
VASCULAR DISEASES
VERTEBRATES
WESTERN REGION