Fulminant transfusion-associated graft-versus-host disease in a premature infant

Journal Article · Mon May 01 04:00:00 EDT 1989 · J. Am. Acad. Dermatol.; (United States)

DOI:https://doi.org/10.1016/S0190-9622(89)70116-X· OSTI ID:6024232

Berger, R S; Dixon, S L

A fatal case of transfusion-associated graft-versus-host disease developed in a premature infant after receiving several blood products, including nonirradiated white blood cells. Transfusion-associated graft-versus-host disease can be prevented. Irradiation of blood products is the least controversial and most effective method. Treatment was unsuccessful in most reported cases of transfusion-associated graft-versus-host disease. Therefore irradiation of blood products before transfusing to patients susceptible to transfusion-associated graft-versus-host disease is strongly recommended.

• Research Organization: Wilford Hall United States Air Force Medical Center, Lackland Air Force Base, TX (USA)
• OSTI ID: 6024232
• Journal Information: J. Am. Acad. Dermatol.; (United States), Journal Name: J. Am. Acad. Dermatol.; (United States) Vol. 20; ISSN JAADD
• Country of Publication: United States
• Language: English

Related Subjects

560120* -- Radiation Effects on Biochemicals
Cells
& Tissue Culture
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
AGE GROUPS
BIOLOGICAL MATERIALS
BLOOD
BODY
BODY FLUIDS
CHILDREN
DOSE-RESPONSE RELATIONSHIPS
ERYTHEMA
GRAFT-HOST REACTION
INFANTS
IRRADIATION
MATERIALS
ORGANS
PATIENTS
SKIN
SYMPTOMS
THERAPY
TRANSFUSIONS