Preliminary toxicological study of Irganox 1010

Technical Report · Mon Oct 01 00:00:00 EDT 1979

DOI:https://doi.org/10.2172/6007213· OSTI ID:6007213

Drake, G A; London, J E; Smith, D M; Thomas, R G

Acute oral LD/sub 50/30/ values for mice and rats receiving Irganox 1010 were found to be greater than 5 g/kg. According to classical guidelines, this material would be considered slightly toxic or practically nontoxic in both species. Skin applicaton studies in rabbits showed the material to be nonirritating. Eye irritation studies, also in the rabbit, showed that Irganox 1010 was a mild but transitory irritant. The sensitizaton study in guinea pigs did not show the material to be deleterious.

• Research Organization: Los Alamos Scientific Lab., NM (USA)
• DOE Contract Number: W-7405-ENG-36
• OSTI ID: 6007213
• Report Number(s): LA-8037-MS
• Country of Publication: United States
• Language: English

Related Subjects

560305* -- Chemicals Metabolism & Toxicology-- Vertebrates-- (-1987)
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMALS
ANTIOXIDANTS
BIOLOGICAL EFFECTS
BODY
DATA
DATA FORMS
EXPERIMENTAL DATA
EYES
GUINEA PIGS
IMMUNITY
INFORMATION
INTAKE
ISOLATED VALUES
MAMMALS
MICE
NUMERICAL DATA
ORAL ADMINISTRATION
ORGANS
RABBITS
RATS
RODENTS
SENSE ORGANS
SINGLE INTAKE
SKIN
TOXICITY
VERTEBRATES