Safety of low anterior resection in the presence of chronic radiation changes in dogs

Journal Article · Wed Jan 01 04:00:00 EST 1986 · Dis. Colon Rectum; (United States)

DOI:https://doi.org/10.1007/BF02555279· OSTI ID:5996816

Meese, D L; Bubrick, M P; Paulson, G L; Feeney, D A; Johnston, G R; Strom, R L; Hitchcock, C R

Thirty mongrel dogs underwent 4000- or 5000-rad single treatment orthovoltage irradiation to the pelvis according to the nominal standard dose equation. Following a resting period of six months, 21 dogs were randomized to low anterior resection with either stapled or handsewn anastomoses. Anastomotic leaks were evaluated on clinical and radiographic grounds. The radiographic leak rate was 81 percent for sutured and 0 percent for stapled anastomoses. The clinical leak rate was 18 percent for sutured and 0 percent for stapled anastomoses. The difference between the 4000- and 5000-rad groups was not significant. The data suggest that late effects of irradiation do not preclude the safe construction of low anterior anastomoses, and that the circular stapling device is superior to hand-sewn techniques.

• Research Organization: Hennepin County Medical Center, Minneapolis, MN
• OSTI ID: 5996816
• Journal Information: Dis. Colon Rectum; (United States), Journal Name: Dis. Colon Rectum; (United States) Vol. 1; ISSN DICRA
• Country of Publication: United States
• Language: English

Related Subjects

560152* -- Radiation Effects on Animals-- Animals
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMALS
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
BODY
DIGESTIVE SYSTEM
DOGS
GASTROINTESTINAL TRACT
INTESTINES
LARGE INTESTINE
LEAKS
MAMMALS
MEDICINE
ORGANS
POST-IRRADIATION THERAPY
RADIATION EFFECTS
RECTUM
SURGERY
THERAPY
VERTEBRATES