Natural variation in the expression of cytochrome P-450 and dimethylnitrosamine demethylase in Drosophila

Journal Article · Fri Sep 28 04:00:00 EDT 1984 · Biochem. Biophys. Res. Commun.; (United States)

DOI:https://doi.org/10.1016/S0006-291X(84)80220-X· OSTI ID:5976043

Waters, L C; Simms, S I; Nix, C E

Electrophoresis of Drosophila microsomes resolves two major heme-containing protein bands with apparent molecular weights of 59,290 (band a) and 55,750 (band b). The hemoproteins in these two bands can account for most of the cytochrome P-450 in the organism. Band a is present in all strains examined: band b is not. Dimethylnitrosamine demethylase, a P-450 enzyme, is a component of band b. 22 references, 2 figures, 1 table.

• Research Organization: Oak Ridge National Lab., TN
• DOE Contract Number: AC05-84OR21400
• OSTI ID: 5976043
• Journal Information: Biochem. Biophys. Res. Commun.; (United States), Journal Name: Biochem. Biophys. Res. Commun.; (United States) Vol. 123:3; ISSN BBRCA
• Country of Publication: United States
• Language: English

Related Subjects

550200* -- Biochemistry
59 BASIC BIOLOGICAL SCIENCES
ANIMALS
ARTHROPODS
CARBOXYLIC ACIDS
CELL CONSTITUENTS
CYTOCHROMES
DIPTERA
DROSOPHILA
ELECTROPHORESIS
ENZYME ACTIVITY
ENZYMES
FLIES
FRUIT FLIES
HEME
HETEROCYCLIC ACIDS
HETEROCYCLIC COMPOUNDS
INSECTS
INVERTEBRATES
MICROSOMES
MOLECULAR WEIGHT
ORGANIC ACIDS
ORGANIC COMPOUNDS
ORGANIC NITROGEN COMPOUNDS
ORGANOIDS
OXIDOREDUCTASES
PIGMENTS
PORPHYRINS
PROTEINS