Radiation exposure and thyroid cancer incidence among Hiroshima and Nagasaki residents

Journal Article · Fri Jan 01 04:00:00 EST 1982 · Natl. Cancer Inst. Monogr.; (United States)

OSTI ID:5975631

Prentice, R L; Kato, H; Yoshimoto, K; Mason, M

The dependence of thyroid cancer incidence on radiation exposure level is examined with the use of tumor registry follow-up data on a life-span cohort of 98,610 Hiroshima and Nagasaki residents. The sample includes 112 clinically evident thyroid cancer cases: 62 in Hiroshima and 50 in Nagasaki. A clear, predominantly linear, increase in thyroid cancer incidence corresponds to increasing levels of gamma radiation to the thyroid gland, whereas neutron exposure could not be shown to contribute further to thyroid cancer risk. The relative risk associated with gamma ray exposure is particularly high among persons who were less than 30 years old at the time of radiation exposure. Limitations on the incidence and dosimetry data are discussed, as well as the ability of the Cox regression method to accommodate some of these limitations.

• Research Organization: Radiation Effects Research Foundation, Hiroshima, Japan
• OSTI ID: 5975631
• Journal Information: Natl. Cancer Inst. Monogr.; (United States), Journal Name: Natl. Cancer Inst. Monogr.; (United States) Vol. 62; ISSN NCIMA
• Country of Publication: United States
• Language: English

Related Subjects

560151* -- Radiation Effects on Animals-- Man
560161 -- Radionuclide Effects
Kinetics
& Toxicology-- Man
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
A-BOMB SURVIVORS
AGE DEPENDENCE
BODY
CARCINOMAS
DISEASES
DOSE-RESPONSE RELATIONSHIPS
DOSES
ENDOCRINE GLANDS
EPIDEMIOLOGY
GLANDS
HUMAN POPULATIONS
NEOPLASMS
ORGANS
POPULATIONS
RADIATION DOSES
THYROID