Multi-institutional in vitro evaluation of commercial /sup 99m/Tc macroaggregated albumin kits

Journal Article · Mon Dec 01 04:00:00 EST 1986 · J. Nucl. Med. Technol.; (United States)

OSTI ID:5973299

Callahan, R J; Swanson, D P; Petry, N A; Beightol, R W; Vaillancourt, J; Dragotakes, S C

Quality control testing of /sup 99m/Tc macroaggregated albumin injection, USP (Tc-MAA) should include determination of radiochemical purity and particle size. The authors evaluated the variability in these parameters in vitro among products from five manufacturers of /sup 99m/Tc-MAA kits. Radiochemical purity, as determined by supernatant activity determinations, varied from 0.5% to 16.0%. Although mean particle size was similar for all products tested, actual particle size distribution varied considerably among products tested.

• Research Organization: Massachusetts General Hospital, Boston
• OSTI ID: 5973299
• Journal Information: J. Nucl. Med. Technol.; (United States), Journal Name: J. Nucl. Med. Technol.; (United States) Vol. 14:4; ISSN JNMTB
• Country of Publication: United States
• Language: English

Related Subjects

38 RADIATION CHEMISTRY, RADIOCHEMISTRY, AND NUCLEAR CHEMISTRY
400702* -- Radiochemistry & Nuclear Chemistry-- Properties of Radioactive Materials
ALBUMINS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
CHEMICAL ANALYSIS
CHROMATOGRAPHY
DRUGS
HOURS LIVING RADIOISOTOPES
IMPURITIES
IN VITRO
INTERMEDIATE MASS NUCLEI
ISOMERIC NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
LABELLED COMPOUNDS
NUCLEI
ODD-EVEN NUCLEI
ORGANIC COMPOUNDS
PARTICLE SIZE
PROTEINS
QUANTITATIVE CHEMICAL ANALYSIS
RADIOCHEMICAL ANALYSIS
RADIOCHROMATOGRAPHY
RADIOISOTOPES
RADIOPHARMACEUTICALS
SEPARATION PROCESSES
SIZE
TECHNETIUM 99
TECHNETIUM ISOTOPES
YEARS LIVING RADIOISOTOPES