Mobile-phase solute mass transfer in supercritical fluid chromatography

Journal Article · Sat Sep 01 04:00:00 EDT 1984 · Anal. Chem.; (United States)

DOI:https://doi.org/10.1021/ac00275a002· OSTI ID:5973231

Springston, S R; Novotny, M

The behavior of several supercritical alkanes was investigated with respect to solute diffusion and mobile-phase mass transfer under a variety of chromatographic conditions. The chromatographic band-broadening method was applied to study diffusion phenomena in uncoated fused-silica tubes using polycyclic aromatic hydrocarbons as model compounds. Possible measurement interferences are discussed. Measured values for the diffusion coefficient (D/sub M/) ranged from 1.0 X 10/sup -4/ to 3.3 X 10/sup -4/ cm/sup 2//s with an estimated precision of 5%. It is observed that D/sub M/ decreased with increasing mobile-phase density. At constant density and temperature, there was no systematic change in D/sub M/ for the C/sub 3-5/ alkanes.

• Research Organization: Indiana Univ., Bloomington
• OSTI ID: 5973231
• Journal Information: Anal. Chem.; (United States), Journal Name: Anal. Chem.; (United States) Vol. 56:11; ISSN ANCHA
• Country of Publication: United States
• Language: English

Related Subjects

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY
400102* -- Chemical & Spectral Procedures
400105 -- Separation Procedures
ALKANES
AROMATICS
CHEMICAL ANALYSIS
CHROMATOGRAPHY
DATA
DIFFUSION
EXPERIMENTAL DATA
HYDROCARBONS
INFORMATION
MASS TRANSFER
NUMERICAL DATA
ORGANIC COMPOUNDS
PHASE STUDIES
POLYCYCLIC AROMATIC HYDROCARBONS
QUANTITATIVE CHEMICAL ANALYSIS
SEPARATION PROCESSES
SOLUBILITY
SOLVENT PROPERTIES
SUPERCRITICAL FLUID CHROMATOGRAPHY