Mutation assay in diploid human lymphoblasts: methodological aspects

Journal Article · Fri Dec 31 23:00:00 EST 1976 · J. Environ. Pathol. Toxicol.; (United States)

OSTI ID:5948609

Thilly, W G; DeLuca, J G; Hoppe, H IV; Liber, H L; Penman, B W

The protocol for a recently developed quantitative assay for mutation at the hgprt locus of human lymphoblasts is presented. Practical problems affecting ease of performance and reliability are discussed with the aim of making the assay available for assessment and possible use in other laboratories.

• Research Organization: Massachusetts Inst. of Tech., Cambridge
• OSTI ID: 5948609
• Journal Information: J. Environ. Pathol. Toxicol.; (United States), Journal Name: J. Environ. Pathol. Toxicol.; (United States) Vol. 1; ISSN JEPTD
• Country of Publication: United States
• Language: English

Related Subjects

560301* -- Chemicals Metabolism & Toxicology-- Cells-- (-1987)
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMAL CELLS
ANIMALS
BIOASSAY
BIOLOGICAL MATERIALS
BLOOD
BLOOD CELLS
BODY FLUIDS
CLONING
CONNECTIVE TISSUE CELLS
DESIGN
LEUKOCYTES
LYMPHOCYTES
MAMMALS
MAN
MATERIALS
MUTAGEN SCREENING
MUTATIONS
PRIMATES
SCREENING
SOMATIC CELLS
VERTEBRATES