Physical properties of VNTR data, and their impact on a test of allelic independence
Journal Article
·
· American Journal of Human Genetics; (United States)
OSTI ID:5941243
- Yale Univ., New Haven, CT (United States)
In this article the authors describe the physical properties of VNTR data, as well as their effects on the two-dimensional distribution of fragment pairs. Tests of independence of alleles at a locus may confound those physical properties with allele independence. A recently proposed test by Geisser and Johnson is an example. The authors show that alleles can be strictly independent, yet the proposed test suggests large violations of allele independence because it is sensitive to well-known electrophoretic phenomena. 7 refs., 4 tabs.
- OSTI ID:
- 5941243
- Journal Information:
- American Journal of Human Genetics; (United States), Journal Name: American Journal of Human Genetics; (United States) Vol. 53:2; ISSN AJHGAG; ISSN 0002-9297
- Country of Publication:
- United States
- Language:
- English
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