Quantitation of left-to-right shunting with Iridium-191m radionuclide angiocardiography

Conference · Wed May 01 00:00:00 EDT 1985 · J. Nucl. Med.; (United States)

OSTI ID:5938915

Treves, S T; Kuruc, A; Fujii, A; Packard, A; Davis, R T

The purpose of this study was to determine whether iridium-191m (Ir-191m) radionuclide angiocardiography (RAC) could be used for the detection and quantitation of left-to-right shunting. In 36 patients' pulmonary-to-systemic flow ratios (Qp:Qs) were calculated using Ir-191m RAC and oximetry at cardiac catheterization. Patients were aged from 4 mos. to 31 yrs. (average 6.5 yrs.). One additional patient was 58 yrs. old. The referral diagnoses included VSD (29 pts.), ASD (3 pts.), PDA (1 pt.) and post-surgery (3 pts.). Ir-191m (tl/2=4.96 sec.) was obtained from an Os-191-)> Ir-191m radionuclide generator. Doses of Ir-191m ranged from 10-100 mCi and were injected as a 1-2 ml bolus in an external jugular vein or into a catheter placed in the inferior vena cava. RAC's were recorded on a computerized gamma camera at 2 frames/sec. This study concludes: Ir-191m RAC allows reliable detection and quantitation of left-to-right shunts. Advantages of Ir-191m include; extremely low radiation exposure to the patient, high photon flux and ability to repeat studies within a short period of time.

• Research Organization: The Children's Hospital and Harvard Medical School, Boston, MA
• OSTI ID: 5938915
• Report Number(s): CONF-850611-; TRN: 87-039272
• Journal Information: J. Nucl. Med.; (United States), Vol. 26:5; Conference: 32. annual meeting of the Society of Nuclear Medicine, Houston, TX, USA, 2 Jun 1985
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
59 BASIC BIOLOGICAL SCIENCES
BLOOD FLOW
RADIOISOTOPE SCANNING
IRIDIUM 191
DIAGNOSTIC USES
RADIOCARDIOGRAPHY
IMAGE PROCESSING
SCINTISCANNING
BLOOD VESSELS
CARDIOVASCULAR SYSTEM
COMPARATIVE EVALUATIONS
DYNAMIC FUNCTION STUDIES
HEART
INFANTS
INTRAVENOUS INJECTION
LUNGS
PATIENTS
PROSTHESES
RELIABILITY
AGE GROUPS
BODY
CARDIOGRAPHY
CHILDREN
COUNTING TECHNIQUES
DIAGNOSTIC TECHNIQUES
HEAVY NUCLEI
INJECTION
INTAKE
IRIDIUM ISOTOPES
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
MEDICAL SUPPLIES
NUCLEI
ODD-EVEN NUCLEI
ORGANS
PROCESSING
RADIOISOTOPES
RESPIRATORY SYSTEM
SECONDS LIVING RADIOISOTOPES
STABLE ISOTOPES
USES
550601* - Medicine- Unsealed Radionuclides in Diagnostics
551001 - Physiological Systems- Tracer Techniques