Quantitation of left-to-right shunting with Iridium-191m radionuclide angiocardiography

Conference · Wed May 01 04:00:00 EDT 1985 · J. Nucl. Med.; (United States)

OSTI ID:5938915

Treves, S T; Kuruc, A; Fujii, A; Packard, A; Davis, R T

The purpose of this study was to determine whether iridium-191m (Ir-191m) radionuclide angiocardiography (RAC) could be used for the detection and quantitation of left-to-right shunting. In 36 patients' pulmonary-to-systemic flow ratios (Qp:Qs) were calculated using Ir-191m RAC and oximetry at cardiac catheterization. Patients were aged from 4 mos. to 31 yrs. (average 6.5 yrs.). One additional patient was 58 yrs. old. The referral diagnoses included VSD (29 pts.), ASD (3 pts.), PDA (1 pt.) and post-surgery (3 pts.). Ir-191m (tl/2=4.96 sec.) was obtained from an Os-191-)> Ir-191m radionuclide generator. Doses of Ir-191m ranged from 10-100 mCi and were injected as a 1-2 ml bolus in an external jugular vein or into a catheter placed in the inferior vena cava. RAC's were recorded on a computerized gamma camera at 2 frames/sec. This study concludes: Ir-191m RAC allows reliable detection and quantitation of left-to-right shunts. Advantages of Ir-191m include; extremely low radiation exposure to the patient, high photon flux and ability to repeat studies within a short period of time.

• Research Organization: The Children's Hospital and Harvard Medical School, Boston, MA
• OSTI ID: 5938915
• Report Number(s): CONF-850611-
• Conference Information: Journal Name: J. Nucl. Med.; (United States) Journal Volume: 26:5
• Country of Publication: United States
• Language: English

Related Subjects

550601* -- Medicine-- Unsealed Radionuclides in Diagnostics
551001 -- Physiological Systems-- Tracer Techniques
59 BASIC BIOLOGICAL SCIENCES
62 RADIOLOGY AND NUCLEAR MEDICINE
AGE GROUPS
BLOOD FLOW
BLOOD VESSELS
BODY
CARDIOGRAPHY
CARDIOVASCULAR SYSTEM
CHILDREN
COMPARATIVE EVALUATIONS
COUNTING TECHNIQUES
DIAGNOSTIC TECHNIQUES
DIAGNOSTIC USES
DYNAMIC FUNCTION STUDIES
HEART
HEAVY NUCLEI
IMAGE PROCESSING
INFANTS
INJECTION
INTAKE
INTRAVENOUS INJECTION
IRIDIUM 191
IRIDIUM ISOTOPES
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
LUNGS
MEDICAL SUPPLIES
NUCLEI
ODD-EVEN NUCLEI
ORGANS
PATIENTS
PROCESSING
PROSTHESES
RADIOCARDIOGRAPHY
RADIOISOTOPE SCANNING
RADIOISOTOPES
RELIABILITY
RESPIRATORY SYSTEM
SCINTISCANNING
SECONDS LIVING RADIOISOTOPES
STABLE ISOTOPES
USES