The sup 194 Os/ sup 194 Ir generator: Production and purification of sup 194 Os
Conference
·
OSTI ID:5925103
Iridium-194 (t{sub {1/2}} = 19.15 h) decays by {beta}-particle emission (E{sub {beta}}{sup max} = 2.236 MeV) and is a potential candidate for radioimmunotherapy (1,2). An important characteristic is availability of carrier-free {sup 194}Ir from {beta}-decay of {sup 194}Os (t{sub {1/2}} = 6 y). The {sup 194}Os parent nuclei is produced in a fission nuclear reactor with double neutron capture on {sup 192}Os (41.0% natural abundance). We report here the preliminary nuclear data for production of {sup 194}OS and discuss the feasibility of producing sufficient quantities of {sup 194}Os required for the fabrication of the large-scale generators for further studies. In addition, we describe a novel gas- thermochromatographic method (GTC) for the one step conversion of metallic Os to OsO{sub 4} and subsequent separation and purification of OsO{sub 4}. 6 refs., 1 fig., 1 tab.
- Research Organization:
- Oak Ridge National Lab., TN (United States)
- Sponsoring Organization:
- DOE; USDOE, Washington, DC (United States)
- DOE Contract Number:
- AC05-84OR21400
- OSTI ID:
- 5925103
- Report Number(s):
- CONF-920418-3-Extd.Abst.; ON: DE92007235
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
38 RADIATION CHEMISTRY, RADIOCHEMISTRY, AND NUCLEAR CHEMISTRY
400703* -- Radiochemistry & Nuclear Chemistry-- Radioisotope Production
550604 -- Medicine-- Unsealed Radionuclides in Therapy-- (1980-)
62 RADIOLOGY AND NUCLEAR MEDICINE
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
CHALCOGENIDES
CHROMATOGRAPHY
DAYS LIVING RADIOISOTOPES
EVEN-EVEN NUCLEI
HEAVY NUCLEI
HOURS LIVING RADIOISOTOPES
IMMUNOLOGY
IMMUNOTHERAPY
INTERNAL CONVERSION RADIOISOTOPES
IRIDIUM 194
IRIDIUM ISOTOPES
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
MEDICINE
NUCLEAR MEDICINE
NUCLEI
ODD-ODD NUCLEI
OSMIUM 194
OSMIUM COMPOUNDS
OSMIUM ISOTOPES
OSMIUM OXIDES
OXIDES
OXYGEN COMPOUNDS
PRODUCTION
PURIFICATION
RADIOIMMUNOLOGY
RADIOIMMUNOTHERAPY
RADIOISOTOPES
RADIOLOGY
RADIOTHERAPY
REFRACTORY METAL COMPOUNDS
SECONDS LIVING RADIOISOTOPES
SEPARATION PROCESSES
SYNTHESIS
THERAPY
THERMOCHROMATOGRAPHY
TRANSITION ELEMENT COMPOUNDS
YEARS LIVING RADIOISOTOPES
400703* -- Radiochemistry & Nuclear Chemistry-- Radioisotope Production
550604 -- Medicine-- Unsealed Radionuclides in Therapy-- (1980-)
62 RADIOLOGY AND NUCLEAR MEDICINE
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
CHALCOGENIDES
CHROMATOGRAPHY
DAYS LIVING RADIOISOTOPES
EVEN-EVEN NUCLEI
HEAVY NUCLEI
HOURS LIVING RADIOISOTOPES
IMMUNOLOGY
IMMUNOTHERAPY
INTERNAL CONVERSION RADIOISOTOPES
IRIDIUM 194
IRIDIUM ISOTOPES
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
MEDICINE
NUCLEAR MEDICINE
NUCLEI
ODD-ODD NUCLEI
OSMIUM 194
OSMIUM COMPOUNDS
OSMIUM ISOTOPES
OSMIUM OXIDES
OXIDES
OXYGEN COMPOUNDS
PRODUCTION
PURIFICATION
RADIOIMMUNOLOGY
RADIOIMMUNOTHERAPY
RADIOISOTOPES
RADIOLOGY
RADIOTHERAPY
REFRACTORY METAL COMPOUNDS
SECONDS LIVING RADIOISOTOPES
SEPARATION PROCESSES
SYNTHESIS
THERAPY
THERMOCHROMATOGRAPHY
TRANSITION ELEMENT COMPOUNDS
YEARS LIVING RADIOISOTOPES