The {sup 194}Os/{sup 194}Ir generator: Production and purification of {sup 194}Os
Iridium-194 (t{sub {1/2}} = 19.15 h) decays by {beta}-particle emission (E{sub {beta}}{sup max} = 2.236 MeV) and is a potential candidate for radioimmunotherapy [1,2]. An important characteristic is availability of carrier-free {sup 194}Ir from {beta}-decay of {sup 194}Os (t{sub {1/2}} = 6 y). The {sup 194}Os parent nuclei is produced in a fission nuclear reactor with double neutron capture on {sup 192}Os (41.0% natural abundance). We report here the preliminary nuclear data for production of {sup 194}OS and discuss the feasibility of producing sufficient quantities of {sup 194}Os required for the fabrication of the large-scale generators for further studies. In addition, we describe a novel gas- thermochromatographic method (GTC) for the one step conversion of metallic Os to OsO{sub 4} and subsequent separation and purification of OsO{sub 4}. 6 refs., 1 fig., 1 tab.
- Research Organization:
- Oak Ridge National Lab., TN (United States)
- Sponsoring Organization:
- USDOE, Washington, DC (United States)
- DOE Contract Number:
- AC05-84OR21400
- OSTI ID:
- 10120231
- Report Number(s):
- CONF-920418--3-Extd.Abst.; ON: DE92007235
- Country of Publication:
- United States
- Language:
- English
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