Effects of cyclohexane, an industrial solvent, on the yeast Saccharomyces cerevisiae and on isolated yeast mitochondria

Journal Article · Sun Jul 01 04:00:00 EDT 1990 · Applied and Environmental Microbiology; (USA)

OSTI ID:5923299

Uribe, S; Rangel, P; Espinola, G; Aguirre, G ^[1]

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1. Universidad Nacional Autonoma de Mexico, Mexico City (Mexico)

Little information on the effects of cyclohexane at the cellular or subcellular level is available. In Saccharomyces cerevisiae, cyclohexane inhibited respiration and diverse energy-dependent processes. In mitochondria isolated from S. cerevisiae, oxygen uptake and ATP synthesis were inhibited, although ATPase activity was not affected. Cyclohexane effects were similar to those reported for beta-pinene and limonene, suggesting that the cyclohexane ring in these monoterpenes may be a determinant for their biological activities.

• OSTI ID: 5923299
• Journal Information: Applied and Environmental Microbiology; (USA), Journal Name: Applied and Environmental Microbiology; (USA) Vol. 56:7; ISSN 0099-2240; ISSN AEMID
• Country of Publication: United States
• Language: English

Related Subjects

560300* -- Chemicals Metabolism & Toxicology
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ALKANES
ATP
CELL CONSTITUENTS
CYCLOALKANES
CYCLOHEXANE
EUMYCOTA
FUNGI
HYDROCARBONS
MICROORGANISMS
MITOCHONDRIA
NUCLEOTIDES
ORGANIC COMPOUNDS
ORGANOIDS
PLANTS
RESPIRATION
SACCHAROMYCES
SACCHAROMYCES CEREVISIAE
TOXICITY
YEASTS