Retention and dosimetry of injected /sup 241/Am in beagles

Journal Article · Fri Nov 30 23:00:00 EST 1984 · Radiat. Res.; (United States)

DOI:https://doi.org/10.2307/3576419· OSTI ID:5885229

Lloyd, R D; Mays, C W; Jones, C W; Atherton, D R; Bruenger, F W; Shabestari, L R; Wrenn, M E

Equations have been derived, from the results of total-body and partial-body counting and ..gamma..-ray counting of individual bones and soft tissues, which describe the retention of injected /sup 241/Am in the liver, in the nonliver tissue (including skeleton), and in the skeleton of young adult beagles. Retention was found to be dependent upon injection level, and different sets of equations were developed for dogs given about (a) 2.8 ..mu..Ci/kg, (b) 0.9 ..mu..Ci/kg, (c) ..mu..Ci/kg, and (d) ..mu..Ci/kg and less. Dosimetry equations based on these retention expressions were derived. Individual bones of 55 beagles were assayed at death for their /sup 241/Am content for a determination of /sup 241/Am distribution within the skeleton.

• Research Organization: Univ. of Utah, Salt Lake City
• DOE Contract Number: AC02-76EV00119
• OSTI ID: 5885229
• Journal Information: Radiat. Res.; (United States), Journal Name: Radiat. Res.; (United States) Vol. 100:3; ISSN RAREA
• Country of Publication: United States
• Language: English

Related Subjects

560172* -- Radiation Effects-- Nuclide Kinetics & Toxicology-- Animals-- (-1987)
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ACTINIDE ISOTOPES
ACTINIDE NUCLEI
ALPHA DECAY RADIOISOTOPES
AMERICIUM 241
AMERICIUM ISOTOPES
ANIMALS
BEAGLES
BODY
CALCULATION METHODS
CARBOXYLIC ACID SALTS
CITRATES
DATA
DIGESTIVE SYSTEM
DOGS
DOSIMETRY
EXPERIMENTAL DATA
FUNCTIONS
GAMMA SPECTROSCOPY
GLANDS
HEAVY NUCLEI
INFORMATION
INJECTION
INTAKE
INTRAVENOUS INJECTION
ISOTOPES
LIVER
MAMMALS
NUCLEI
NUMERICAL DATA
ODD-EVEN NUCLEI
ORGANS
RADIOISOTOPES
RADIONUCLIDE KINETICS
RETENTION
RETENTION FUNCTIONS
SKELETON
SPECTROSCOPY
VERTEBRATES
YEARS LIVING RADIOISOTOPES