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U.S. Department of Energy
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Positron emission tomography

Journal Article · · Crit. Rev. Biomed. Eng.; (United States)
OSTI ID:5881889

Positron computed tomography allows for the in vivo measurement of the regional tissue concentration of positron-emitting radionuclides such as /sup 15/O, /sup 11/C, /sup 13/N, and /sup 18/F. By using different tracers, a variety of metabolic processes can be quantitated. These include blood flow, oxygen utilization, glucose utilization, amino acid transport, blood volume, cation exchange, pH, and others. This review will contain three sections. First, the principles of positron computed tomography and the progress in instrumentation will be discussed. Second, tracer models will be analyzed. These models are vital in the extraction of physiological data from the measurements of activity. Finally, clinical studies will be evaluated in terms of new pathophysiological information obtained. 271 references.

OSTI ID:
5881889
Journal Information:
Crit. Rev. Biomed. Eng.; (United States), Journal Name: Crit. Rev. Biomed. Eng.; (United States) Vol. 2; ISSN CRBED
Country of Publication:
United States
Language:
English