Regional left ventricular filling: Does it reflect diastolic abnormalities in contiguous areas of myocardium

Journal Article · Wed Feb 01 04:00:00 EST 1989 · J. Nucl. Med.; (United States)

OSTI ID:5821234

Brown, Jr, E J; Idoine, J; Swinford, R D; Pollack, W M; Lawson, W E; Shatkin, B; Oster, Z H; Atkins, H L; Cohn, P F

To test the hypothesis that regional left ventricular filling reflects diastolic changes in contiguous areas of myocardium, we performed radionuclide ventriculograms on normal subjects, patients with left anterior descending coronary artery disease, and patients with anteroseptal myocardial infarctions. We reasoned that because diastolic properties of the anteroseptal myocardium should be different in the three groups of patients, regional filling in the anteroseptal area of the left ventricle should also be different, if regional filling does, indeed, reflect diastolic changes in the adjacent myocardium. While anteroseptal regional filling in the normal subjects was different than regional filling in the two patient groups, the degree of filling abnormality was similar in patients with and without myocardial infarctions. Our results suggest that regional left ventricular filling is not exclusively determined by diastolic changes in contiguous areas of myocardium.

• Research Organization: State Univ. of New York Health Sciences Center, Stony Brook (USA)
• OSTI ID: 5821234
• Journal Information: J. Nucl. Med.; (United States), Journal Name: J. Nucl. Med.; (United States) Vol. 30:2; ISSN JNMEA
• Country of Publication: United States
• Language: English

Related Subjects

550601* -- Medicine-- Unsealed Radionuclides in Diagnostics
62 RADIOLOGY AND NUCLEAR MEDICINE
BIOLOGICAL MATERIALS
BLOOD
BLOOD CELLS
BODY
BODY FLUIDS
CARDIOVASCULAR DISEASES
CARDIOVASCULAR SYSTEM
CONTRACTION
DIAGNOSIS
DISEASES
ERYTHROCYTES
HEART
IMAGE PROCESSING
ISOTOPES
MATERIALS
MYOCARDIAL INFARCTION
ORGANS
PATIENTS
PROCESSING
TECHNETIUM ISOTOPES