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Steady-state relationship of calcium-45 between bone and blood: differences in growing dogs, chicks, and rats

Journal Article · · Science (Washington, D.C.); (United States)
In young animals that had received multiple doses of calcium-45, a constant ratio of calcium-45 specific activity in blood to that in bone was found in growing dogs and chicks but not in rats. This steady-state relationship of calcium-45 between bone and blood suggests that during growth in dogs and chicks most of the skeletal calcium is an active state of turnover. In growing rats, after the first 2 weeks of life, the blood/bone ratio of calcium-45 decreases due to a decrease in bone resorption.
Research Organization:
Case Western Reserve Univ., Cleveland, OH
OSTI ID:
5801523
Journal Information:
Science (Washington, D.C.); (United States), Journal Name: Science (Washington, D.C.); (United States) Vol. 214; ISSN SCIEA
Country of Publication:
United States
Language:
English