Effects of argon, dye, and Nd:YAG lasers on epidermis, dermis, and venous vessels

Journal Article · Wed Jan 01 04:00:00 EST 1986 · Lasers Surg. Med.; (United States)

DOI:https://doi.org/10.1002/lsm.1900060118· OSTI ID:5801019

Landthaler, M; Haina, D; Brunner, R; Waidelich, W; Braun-Falco, O

The aim of the present study, which was performed at the dorsal aspects of the ears of guinea pigs, was to compare effects of different lasers on epidermis, dermis, and small venous vessels. Irradiations were performed with argon, dye, and Nd:YAG lasers. In the first series tissue repair processes were studied after argon laser application. Laser defects were excised after 1, 4, 8, and 14 days and were prepared for routine histological examination. The breadth of epidermal defect and extent of dermal coagulation and occlusion of vessels by thrombus formation were examined histologically. In a second series parameters of irradiation (ie, exposure time, laser power) of the three different lasers were changed systematically. Laser-induced morphological tissue changes could be best observed 24 hours after irradiation. Each of the lasers led to occlusion of vessels by thrombus formation and also coagulated epidermis and dermis. The extent of dermal and epidermal coagulation was less pronounced after dye laser application. Using short exposure times it was possible to reduce the extent of epidermal damage caused by argon and Nd:YAG lasers. Only 50-msec dye laser pulses led to intravascular thrombus formation without epidermal and dermal damage.

• Research Organization: Univ. of Munich, Germany, F.R.
• OSTI ID: 5801019
• Journal Information: Lasers Surg. Med.; (United States), Journal Name: Lasers Surg. Med.; (United States) Vol. 1; ISSN LSMED
• Country of Publication: United States
• Language: English

Related Subjects

550600 -- Medicine
560400* -- Other Environmental Pollutant Effects
62 RADIOLOGY AND NUCLEAR MEDICINE
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMAL TISSUES
ANIMALS
BIOLOGICAL EFFECTS
BIOLOGICAL RECOVERY
BIOLOGICAL REPAIR
BLOOD VESSELS
BODY
CARDIOVASCULAR DISEASES
CARDIOVASCULAR SYSTEM
DISEASES
DYE LASERS
EPIDERMIS
EPITHELIUM
GUINEA PIGS
LASERS
LIQUID LASERS
MAMMALS
MORPHOLOGICAL CHANGES
NEODYMIUM LASERS
ORGANS
RECOVERY
REPAIR
RODENTS
SKIN
SOLID STATE LASERS
THROMBOSIS
TISSUES
VASCULAR DISEASES
VEINS
VERTEBRATES