Multimodality therapy of favorable prognosis non-Hodgkin's lymphoma
Journal Article
·
· Int. J. Radiat. Oncol., Biol. Phys.; (United States)
- Univ. of Iowa Hospitals, Iowa City
Twenty-seven previously untreated patients with favorable prognosis non-Hodgkin's lymphoma were treated with a combination of total body irradiation followed by cyclophosphamide - vincristine - prednisone (CVP). The dose of total body irradiation was planned to be 150 rad followed by 6 cycles of chemotherapy. The complete response rate was 59%; the complete plus partial response rate, 93%. The 50% disease-free survival was 8 months. The actuarial projected 5 year survival was 60% and the disease-free survival at 5 years was 27%. The program was well tolerated by the majority of patients. It is possible for some patients with favorable non-Hodgkin's lymphomas to achieve prolonged periods of disesase-free survival when treated with combinations of irradiation plus chemotherapy.
- OSTI ID:
- 5775711
- Journal Information:
- Int. J. Radiat. Oncol., Biol. Phys.; (United States), Journal Name: Int. J. Radiat. Oncol., Biol. Phys.; (United States) Vol. 9:7; ISSN IOBPD
- Country of Publication:
- United States
- Language:
- English
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Journal Article
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Tue Sep 01 00:00:00 EDT 1981
· Blood; (United States)
·
OSTI ID:5365894
Related Subjects
550600 -- Medicine
550603* -- Medicine-- External Radiation in Therapy-- (1980-)
560151 -- Radiation Effects on Animals-- Man
62 RADIOLOGY AND NUCLEAR MEDICINE
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ADRENAL HORMONES
ALKALOIDS
ALKYLATING AGENTS
ANTIMITOTIC DRUGS
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
CHEMOTHERAPY
CORTICOSTEROIDS
DISEASES
DRUGS
ENDOXAN
EXTERNAL IRRADIATION
GLUCOCORTICOIDS
HORMONES
HYDROXY COMPOUNDS
IMMUNITY
IMMUNOSUPPRESSIVE DRUGS
IRRADIATION
KETONES
LYMPHOMAS
MEDICINE
NEOPLASMS
NUCLEAR MEDICINE
ONCOVIN
ORGANIC COMPOUNDS
PATIENTS
PREDNISONE
PREGNANES
RADIATION EFFECTS
RADIOLOGY
RADIOTHERAPY
SIDE EFFECTS
STEROID HORMONES
STEROIDS
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WHOLE-BODY IRRADIATION
550603* -- Medicine-- External Radiation in Therapy-- (1980-)
560151 -- Radiation Effects on Animals-- Man
62 RADIOLOGY AND NUCLEAR MEDICINE
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ADRENAL HORMONES
ALKALOIDS
ALKYLATING AGENTS
ANTIMITOTIC DRUGS
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
CHEMOTHERAPY
CORTICOSTEROIDS
DISEASES
DRUGS
ENDOXAN
EXTERNAL IRRADIATION
GLUCOCORTICOIDS
HORMONES
HYDROXY COMPOUNDS
IMMUNITY
IMMUNOSUPPRESSIVE DRUGS
IRRADIATION
KETONES
LYMPHOMAS
MEDICINE
NEOPLASMS
NUCLEAR MEDICINE
ONCOVIN
ORGANIC COMPOUNDS
PATIENTS
PREDNISONE
PREGNANES
RADIATION EFFECTS
RADIOLOGY
RADIOTHERAPY
SIDE EFFECTS
STEROID HORMONES
STEROIDS
THERAPY
WHOLE-BODY IRRADIATION