Adaptation of intestinal calcium absorption: parathyroid hormone and vitamin D metabolism

Journal Article · Mon May 01 04:00:00 EDT 1978 · Arch. Biochem. Biophys.; (United States)

DOI:https://doi.org/10.1016/0003-9861(78)90368-5· OSTI ID:5731780

Ribovich, M L; DeLuca, H F

It has already been demonstrated that the adaptation of intestinal calcium absorption of rats on a low calcium diet can be eliminated by thyroparathyoidectomy plus parathyroid hormone administration. It therefore appears likely that the modulation of intestinal calcium absorption by dietary calcium is mediated by the parathyroid glands and the renal biogenesis of 1,25-dihydoxyvitamin D/sub 3/. Changes in the other unknown vitamin D metabolite levels as a result of dietary calcium are also modified by thyroparathyroidectomy and parathyroid hormone administration, but the effect of these metabolites on intestinal calcium transport is unknown.

• Research Organization: Univ. of Wisconsin, Madison
• OSTI ID: 5731780
• Journal Information: Arch. Biochem. Biophys.; (United States), Journal Name: Arch. Biochem. Biophys.; (United States) Vol. 188:1; ISSN ABBIA
• Country of Publication: United States
• Language: English

Related Subjects

550201 -- Biochemistry-- Tracer Techniques
550501 -- Metabolism-- Tracer Techniques
551001* -- Physiological Systems-- Tracer Techniques
59 BASIC BIOLOGICAL SCIENCES
ALKALINE EARTH METALS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BODY
CALCIUM
CHOLECALCIFEROL
DIET
ELEMENTS
ENDOCRINE GLANDS
GLANDS
HORMONES
HYDROGEN ISOTOPES
INTESTINAL ABSORPTION
ISOTOPES
LIGHT NUCLEI
METABOLISM
METALS
NUCLEI
ODD-EVEN NUCLEI
ORGANS
PARATHORMONE
PARATHYROID GLANDS
PEPTIDE HORMONES
RADIOISOTOPES
TRITIUM
UPTAKE
VITAMIN D
VITAMINS
YEARS LIVING RADIOISOTOPES