Effect of low-level exposure to ozone on arterial oxygenation in humans

Journal Article · Tue May 01 04:00:00 EDT 1979 · Am. Rev. Respir. Dis.; (United States)

OSTI ID:5723897

Linn, W S; Jones, M P; Bachmayer, E A; Clark, K W; Karuza, S K; Hackney, J D

Arterial blood oxygenation effects from exposure to 0.2 ppM of ozone in purified air for 2 hours with intermittent light exercise and heat stress were studied. Similar exposures to purified air alone provided control data. In 12 healthy volunteers, blood gases were measured before and during exposure via an indwelling brachial cannula. Six of these subjects and 6 other subjects underwent separate similar studies in which arterialized earlobe capillary blood was sampled. Arterial Po2 and alveolar-arterial Po2 differences varied significantly among different experimental conditions, but the variability was similar in the presence or absence of ozone. Small significant variations in body temperaure were observed; these did not appear to be sufficient to affect blood gas measurements substantially. Over-all, we found no evidence for an adverse effect of the exposure to ozone on arterial oxygenation.

• Research Organization: Univ. of Southern California, Downey
• OSTI ID: 5723897
• Journal Information: Am. Rev. Respir. Dis.; (United States), Journal Name: Am. Rev. Respir. Dis.; (United States) Vol. 119:5; ISSN ARRDA
• Country of Publication: United States
• Language: English

Related Subjects

560306* -- Chemicals Metabolism & Toxicology-- Man-- (-1987)
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMALS
ARTERIES
BIOLOGICAL EFFECTS
BIOLOGICAL MATERIALS
BLOOD
BLOOD VESSELS
BODY
BODY FLUIDS
CARDIOVASCULAR SYSTEM
ELEMENTS
MAMMALS
MAN
MATERIALS
NONMETALS
ORGANS
OXYGEN
OZONE
PRIMATES
TOXICITY
TRACE AMOUNTS
VERTEBRATES