Derivatized cyclodextrins immobilized on fused-silica capillaries for enantiomeric separations via capillary electrophoresis, gas chromatography, or supercritical fluid chromatography

Journal Article · Thu Apr 15 00:00:00 EDT 1993 · Analytical Chemistry (Washington); (United States)

DOI:https://doi.org/10.1021/ac00056a028· OSTI ID:5717549

Armstrong, D W; Tang, Y ^[1]; Ward, T; Nichols, M ^[2]

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1. Univ. of Missouri, Rolla (United States)
2. Millsaps College, Jackson, MS (United States)

Clearly capillary columns containing immobilized cyclodextrin coatings will be useful for a variety of separation methods. Although hardy, they will not completely replace the coated columns for GC separations. This is because the enantioselectivity of the bonded column is somewhat different from many of the coated columns. Also there is a greater variety of coated columns, which means a greater variety of enantiomers and other compounds can be resolved. Finally, for lower temperature GC separations, the performance and enantioselectivity of the coated columns sometimes exceeds that of the bonded-phase columns. However for longevity and performance at high temperatures, with supercritical fluids, or in the presence of solvents, the immobilized cyclodextrin-based stationary phase is not only effective, but often essential. 10 refs., 4 figs., 2 tabs.

• DOE Contract Number: FG02-88ER13819
• OSTI ID: 5717549
• Journal Information: Analytical Chemistry (Washington); (United States), Vol. 65:8; ISSN 0003-2700
• Country of Publication: United States
• Language: English

Related Subjects

37 INORGANIC
ORGANIC
PHYSICAL AND ANALYTICAL CHEMISTRY
DEXTRIN
DERIVATIZATION
ENANTIOMORPHS
ELECTROPHORESIS
GAS CHROMATOGRAPHY
SUPERCRITICAL FLUID CHROMATOGRAPHY
CAPILLARIES
EXPERIMENTAL DATA
SILICA
BLOOD VESSELS
BODY
CARBOHYDRATES
CARDIOVASCULAR SYSTEM
CHALCOGENIDES
CHEMICAL REACTIONS
CHROMATOGRAPHY
DATA
INFORMATION
MINERALS
NUMERICAL DATA
ORGANIC COMPOUNDS
ORGANS
OXIDE MINERALS
OXIDES
OXYGEN COMPOUNDS
POLYSACCHARIDES
SACCHARIDES
SEPARATION PROCESSES
SILICON COMPOUNDS
SILICON OXIDES
400102* - Chemical & Spectral Procedures
400400 - Electrochemistry