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Molecular recognition of enantiomeric hydrocarbons by liquid functionalized cyclodextrins: A new approach for geochemical research

Technical Report ·
OSTI ID:5733454

Our work involves theoretical and mechanistic binding studies to micelles and cyclodextrin, novel separation and detection studies, and chiral recognition and separation studies. Both inclusion behavior and noninclusion'' association behavior of small solutes to cyclodextrins were evaluated. In the case of traditional inclusion-behavior, equations were derived which take into account the formation of multiple complexation. Standard enthalpies and equilibrium constants were measured by calorimetry for a series of different phenols to substituted and native cyclodextrins. Substitution effects were significant and all of the effects studied showed a considerable amount of entropy-enthalpy compensation. Two cases were observed in which the cyclodextrin-solute association may not involve inclusion complexation.

Research Organization:
Missouri Univ., Rolla, MO (USA)
Sponsoring Organization:
DOE; USDOE, Washington, DC (USA)
DOE Contract Number:
FG02-88ER13819
OSTI ID:
5733454
Report Number(s):
DOE/ER/13819-1; ON: DE91012902
Country of Publication:
United States
Language:
English