PET as a tool in the clinical evaluation of pituitary adenomas

Journal Article · Mon Apr 01 04:00:00 EST 1991 · Journal of Nuclear Medicine; (United States)

OSTI ID:5670729

Bergstroem, M M; Muhr, C; Lundberg, P O; B4, Langstroem ^[1]

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1. Uppsala Univ. PET Center (Sweden)

Positron emission tomography (PET) was used in over 400 examinations in patients with pituitary adenoma. It was demonstrated that PET with carbon-11-methionine can give valuable complementary information in the diagnosis of this tumor due to PET's ability to adequately depict viable tumor tissue in contrast to fibrosis, cysts and necrosis. Furthermore, PET with dopamine D2 receptor ligands can characterize the degree of receptor binding and thus give information as to the prerequisites for dopamine agonist treatment. Most important is the very high sensitivity given by PET with carbon-11-methionine in the evaluation of treatment effects. It is concluded that when properly used PET can be fully justified in the clinical handling of patients with pituitary adenomas and other intracranial tumors.

• OSTI ID: 5670729
• Journal Information: Journal of Nuclear Medicine; (United States), Journal Name: Journal of Nuclear Medicine; (United States) Vol. 32:4; ISSN 0161-5505; ISSN JNMEA
• Country of Publication: United States
• Language: English

Related Subjects

550601* -- Medicine-- Unsealed Radionuclides in Diagnostics
62 RADIOLOGY AND NUCLEAR MEDICINE
ADENOMAS
AMINO ACIDS
BODY
CARBON ISOTOPES
CARBOXYLIC ACIDS
COMPUTERIZED TOMOGRAPHY
DIAGNOSIS
DIAGNOSTIC TECHNIQUES
DIAGNOSTIC USES
DISEASES
DRUGS
EMISSION COMPUTED TOMOGRAPHY
ENDOCRINE GLANDS
GLANDS
ISOTOPES
LIPOTROPIC FACTORS
METHIONINE
NEOPLASMS
ORGANIC ACIDS
ORGANIC COMPOUNDS
ORGANIC SULFUR COMPOUNDS
ORGANS
PATIENTS
PITUITARY GLAND
POSITRON COMPUTED TOMOGRAPHY
TOMOGRAPHY
USES