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Mechanism of bone marrow lymphoid reaction in irradiated rats during period of restoration of hemopoiesis

Journal Article · · Radiobiology (USSR) (Engl. Transl.); (United States)
OSTI ID:5663023
In experiments on rats exposed to radiation in a dosage of 600 rad, it was demonstrated that there is an increase in lymphoid element content during the period of regeneration of hemopoiesis (10th to 15th day) in bone marrow. The dynamics of morphological changes cytometry results, studies of proliferative activity, capacity for uptake of /sup 3/H-thymidine and hydrolytic enzyme levels in lymphoid cells of bone marrow, thymus, spleen and lymph nodes, as well as experiments conducted on thymectomized and splenectomized animals, indicate that there is proliferation and maturation of lymphocytes in bone marrow at this time.
Research Organization:
Tomsk State Medical Inst., USSR
OSTI ID:
5663023
Journal Information:
Radiobiology (USSR) (Engl. Transl.); (United States), Journal Name: Radiobiology (USSR) (Engl. Transl.); (United States) Vol. 19:1; ISSN RADBA
Country of Publication:
United States
Language:
English

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