The effects of a fractionated gamma irradiation on life shortening and disease incidence in BALB/c mice

Journal Article · Sun May 01 04:00:00 EDT 1983 · Radiat. Res.; (United States)

DOI:https://doi.org/10.2307/3575970· OSTI ID:5638888

Maisin, J R; Wambersie, A; Gerber, G B; Mattelin, G; Lambiet-Collier, M; Gueulette, J

BALB/c male mice (12 weeks old) were exposed to a single or fractionated exposure of /sup 137/Cs ..gamma.. rays. The fractionated dose was split into 10 equal doses delivered at an interval of 1 day. The causes and possible causes of spontaneous death were ascertained by autopsy and histological examination, and the data were treated by competing risk anaysis. Life shortening followed a linear dose dependency and was about the same for fractionated (38.1 +/- 3.1 days/Gy) as for single (46.2 +/- 4.3 days/Gy) exposure. Death from tumor disease was enhanced and that from nonstochastic lung and kidney diseases was reduced after fractionated compared to single exposure.

• OSTI ID: 5638888
• Journal Information: Radiat. Res.; (United States), Journal Name: Radiat. Res.; (United States) Vol. 94:2; ISSN RAREA
• Country of Publication: United States
• Language: English

Related Subjects

560152* -- Radiation Effects on Animals-- Animals
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ALKALI METAL ISOTOPES
ANIMALS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
CESIUM 137
CESIUM ISOTOPES
DATA
DELAYED RADIATION EFFECTS
DISEASE INCIDENCE
DOSE-RESPONSE RELATIONSHIPS
ELECTROMAGNETIC RADIATION
EXPERIMENTAL DATA
FRACTIONATED IRRADIATION
GAMMA RADIATION
INFORMATION
IONIZING RADIATIONS
IRRADIATION
ISOTOPES
LIFE SPAN
MAMMALS
MICE
NUCLEI
NUMERICAL DATA
ODD-EVEN NUCLEI
RADIATION EFFECTS
RADIATIONS
RADIOISOTOPES
RODENTS
SURVIVAL TIME
VERTEBRATES
YEARS LIVING RADIOISOTOPES