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Life shortening and disease incidence in BALB/c mice following a single d(50)-Be neutron or gamma exposure

Journal Article · · Radiat. Res.; (United States)
DOI:https://doi.org/10.2307/3575971· OSTI ID:5578493
Male BALB/c mice, 12 weeks old, were given a single exposure of either /sup 137/Cs ..gamma.. rays or d(50)-Be neutrons at a dose rate of 3 Gy/min. The animals were kept until death, and causes of death or possible causes of death were ascertained by autopsy and histology. The data were evaluated by competing risk methods. The survival time dose-effect curve for both types of exposure was linear and did not differ significantly (slopes: 55.8 +/- 4.0 days/Gy for neutrons and 46.2 +/- 4.3 days/Gy for ..gamma.. rays). The incidence of different diseases also was similar for both groups expect that more carcinomas, sarcomas, and myeloid leukemias seemed to occur after neutron exposure and that nonstochastic lung and kidney diseases seemed to arise at lower doses.
OSTI ID:
5578493
Journal Information:
Radiat. Res.; (United States), Journal Name: Radiat. Res.; (United States) Vol. 94:2; ISSN RAREA
Country of Publication:
United States
Language:
English