Displacement effect in multicomponent chromatography
Journal Article
·
· Industrial and Engineering Chemistry Research; (United States)
OSTI ID:5637461
- Purdue Univ., West Lafayette, IN (US)
The study of interference effects is of fundamental importance in understanding multicomponent chromatography. In this paper a displacement effect is examined and shown to be able to explain the dominating interference effects in three major modes of chromatography - frontal, elution, and displacement - involving competitive isotherms. It is concluded that the concentration profile of a component usually becomes sharper due to the displacement effect from another component, while the concentration front of the displacer is usually diffused. Five factors that escalate the displacement effect in multicomponent elution were investigated. A binary elution with a competing modifier in the mobile phase was also discussed. This study was carried out using computer simulations based on a general nonlinear multicomponent rate equation model that considers axial dispersion, external mass transfer, intraparticle diffusion, and Langmuir isotherms. The use of the general model helps the visualization of the multicomponent interactions in chromatography under mass transfer conditions.
- Sponsoring Organization:
- NSF; National Science Foundation, Washington, DC (United States)
- OSTI ID:
- 5637461
- Journal Information:
- Industrial and Engineering Chemistry Research; (United States), Journal Name: Industrial and Engineering Chemistry Research; (United States) Vol. 36:8; ISSN 0888-5885; ISSN IECRE
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
02 PETROLEUM
020400 -- Petroleum-- Processing
37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY
400105* -- Separation Procedures
BINARY MIXTURES
CHEMICAL REACTION KINETICS
CHROMATOGRAPHY
COMPUTERIZED SIMULATION
DIFFERENTIAL EQUATIONS
DIFFUSION
DISPERSIONS
DISPLACEMENT FLUIDS
EQUATIONS
EQUATIONS OF MOTION
FLOW VISUALIZATION
FLUID FLOW
FLUID MECHANICS
FLUIDS
INDUSTRIAL PLANTS
ISOTHERMAL PROCESSES
KINETICS
MASS TRANSFER
MECHANICS
MIXTURES
NONLINEAR PROBLEMS
PARTIAL DIFFERENTIAL EQUATIONS
PETROLEUM REFINERIES
PHASE STUDIES
REACTION KINETICS
SEPARATION PROCESSES
SIMULATION
TONKS-LANGMUIR THEORY
020400 -- Petroleum-- Processing
37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY
400105* -- Separation Procedures
BINARY MIXTURES
CHEMICAL REACTION KINETICS
CHROMATOGRAPHY
COMPUTERIZED SIMULATION
DIFFERENTIAL EQUATIONS
DIFFUSION
DISPERSIONS
DISPLACEMENT FLUIDS
EQUATIONS
EQUATIONS OF MOTION
FLOW VISUALIZATION
FLUID FLOW
FLUID MECHANICS
FLUIDS
INDUSTRIAL PLANTS
ISOTHERMAL PROCESSES
KINETICS
MASS TRANSFER
MECHANICS
MIXTURES
NONLINEAR PROBLEMS
PARTIAL DIFFERENTIAL EQUATIONS
PETROLEUM REFINERIES
PHASE STUDIES
REACTION KINETICS
SEPARATION PROCESSES
SIMULATION
TONKS-LANGMUIR THEORY