Roles of pH, titratable acid, and specific chemical composition in mediating effects of acid aerosols on the airways. Final report
Technical Report
·
OSTI ID:5630912
The investigators exposed asthmatic subjects to aerosols of sulfuric and hydrochloric acid to study the relative importance of different factors on the bronchoconstrictor potency of acid aerosols. The investigators also compared the bronchoconstrictor potency of sulfite aerosols inhaled at 3 different pHs to examine the relative importance of the two different ionic forms of sulfite and of the sulfur dioxide gas with which these ions are in equilibrium. Finally, to determine if other measurements would be more-sensitive indicators of the effects of acid aerosols than bronchoconstriction, they examined the effects of exposure to acid aerosols on guinea pigs.
- Research Organization:
- California Univ., San Francisco, CA (USA). Lung Biology Center
- OSTI ID:
- 5630912
- Report Number(s):
- PB-89-181770/XAB
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
560300* -- Chemicals Metabolism & Toxicology
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
AEROSOLS
ASTHMA
CHEMICAL ANALYSIS
COLLOIDS
DISEASES
DISPERSIONS
DOCUMENT TYPES
HAZARDS
HEALTH HAZARDS
HYDROCHLORIC ACID
HYDROGEN COMPOUNDS
INORGANIC ACIDS
LABORATORY ANIMALS
PH VALUE
PROGRESS REPORT
PUBLIC HEALTH
QUANTITATIVE CHEMICAL ANALYSIS
RESPIRATORY SYSTEM
RESPIRATORY SYSTEM DISEASES
SOLS
SULFURIC ACID
VOLUMETRIC ANALYSIS
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
AEROSOLS
ASTHMA
CHEMICAL ANALYSIS
COLLOIDS
DISEASES
DISPERSIONS
DOCUMENT TYPES
HAZARDS
HEALTH HAZARDS
HYDROCHLORIC ACID
HYDROGEN COMPOUNDS
INORGANIC ACIDS
LABORATORY ANIMALS
PH VALUE
PROGRESS REPORT
PUBLIC HEALTH
QUANTITATIVE CHEMICAL ANALYSIS
RESPIRATORY SYSTEM
RESPIRATORY SYSTEM DISEASES
SOLS
SULFURIC ACID
VOLUMETRIC ANALYSIS