Modified flame ionization detector for supercritical fluid chromatography

Journal Article · Sun Apr 01 04:00:00 EST 1984 · Anal. Chem.; (United States)

DOI:https://doi.org/10.1021/ac00268a060· OSTI ID:5618094

Rawdon, M G

The use of fluids above their critical point as chromatographic mobile phases has been receiving increased attention recently. Supercritical fluids have physical properties intermediate between liquids and gases, which give them favorable behavior for the transport of solutes in a chromatographic column. Advantages of supercritical fluid chromatography (SFC) include fast analyses, increased resolution per unit time compared to HPLC, and ease of fraction collecting. Detection in SFC is certainly one of the limiting aspects of the technique, as it often is in HPLC. There exists a need for a sensitive, universally responsive detector. In gas chromatography, several detectors are available to meet this need including the flame ionization detector (FID) and the mass spectrometer. Attempts to adapt this technology to liquid chromatography have met with limited success. Moving wire/belt FID's are useful for nonvolatile solutes but have never made a significant market impact. The problems of interfacing a liquid chromatograph to a mass spectrometer are well documented and this is currently an area of great effort. Carbon dioxide as the mobile phase in SFC offers the advantage that an FID can be connected directly, since it gives no response in this detector. There exist literature on the use of an FID for SFC, but details of its construction were not given. A patent has been issued for an FID for SFC, but the detector was never commercially available. For laboratories who cannot or choose not to construct such a detector, here the modifications necessary to adapt a commercial gas chromatographic FID for SFC are described.

• Research Organization: Texaco Research Center, Beacon, NY
• DOE Contract Number: AC02-76CH00016
• OSTI ID: 5618094
• Journal Information: Anal. Chem.; (United States), Journal Name: Anal. Chem.; (United States) Vol. 56:4; ISSN ANCHA
• Country of Publication: United States
• Language: English

Related Subjects

02 PETROLEUM
023000 -- Petroleum-- Properties & Composition
37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY
400102* -- Chemical & Spectral Procedures
400104 -- Spectral Procedures-- (-1987)
ALKANES
AROMATICS
CARBON COMPOUNDS
CARBON DIOXIDE
CARBON OXIDES
CHALCOGENIDES
CHEMICAL ANALYSIS
CHROMATOGRAPHY
DATA
DIESEL FUELS
EXPERIMENTAL DATA
FLAME PHOTOMETRY
GAS CHROMATOGRAPHY
HYDROCARBONS
INFORMATION
NUMERICAL DATA
ORGANIC COMPOUNDS
OXIDES
OXYGEN COMPOUNDS
PETROLEUM PRODUCTS
PHOTOMETRY
QUANTITATIVE CHEMICAL ANALYSIS
SEPARATION PROCESSES
SUPERCRITICAL FLUID CHROMATOGRAPHY