Chromatography with supercritical fluids

Journal Article · Fri Mar 13 04:00:00 EST 1987 · Science (Washington, D.C.); (United States)

DOI:https://doi.org/10.1126/science.235.4794.1342· OSTI ID:6950985

Lee, M L; Markides, K E

In supercritical fluid chromatography (SFC) the mobile phase is neither a gas nor a liquid, but is a supercritical fluid. As a result of the unique properties of supercritical fluids, SFC is rapidly becoming a prominent separation technique for the analysis of reactive, thermally labile, and nonvolatile compounds. This article reviews the history, instrumentation, and practice of the technique. Particular emphasis is placed on the different programming methods that allow elution to be selectively controlled in ways that are unique to SFC. 43 refs., 5 figs., 3 tabs.

• Research Organization: Brigham Young Univ., Provo, UT
• OSTI ID: 6950985
• Journal Information: Science (Washington, D.C.); (United States), Journal Name: Science (Washington, D.C.); (United States) Vol. 235:4794; ISSN SCIEA
• Country of Publication: United States
• Language: English

Related Subjects

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY
400105* -- Separation Procedures
AMMONIA
CARBON COMPOUNDS
CARBON DIOXIDE
CARBON OXIDES
CHALCOGENIDES
CHROMATOGRAPHY
DENSITY
FREONS
GAS CHROMATOGRAPHY
HALOGENATED ALIPHATIC HYDROCARBONS
HYDRIDES
HYDROGEN COMPOUNDS
LIQUID COLUMN CHROMATOGRAPHY
NITROGEN COMPOUNDS
NITROGEN HYDRIDES
NITROGEN OXIDES
NITROUS OXIDE
ORGANIC COMPOUNDS
ORGANIC HALOGEN COMPOUNDS
OXIDES
OXYGEN COMPOUNDS
PHYSICAL PROPERTIES
SEPARATION PROCESSES
SOLVENT PROPERTIES
SUPERCRITICAL FLUID CHROMATOGRAPHY
SUPERCRITICAL STATE