Supercritical fluid chromatography: mass spectrometry

Conference · Sun Aug 01 04:00:00 EDT 1982

OSTI ID:7031650

Smith, R D; Fjeldsted, J; Lee, M L

A new interface for capillary column supercritical fluid chromatography-mass spectrometry (SFC-MS) is described and initial results are presented. The advantages of SFC include the ability to separate high molecular weight, nonvolatile, and thermally unstable compounds not amenable to GC. A capillary column SFC-MS interface can replace HPLC-MS in most applications and has advantages due to the higher possible chromatographic efficiency, mobile phase volatility, and the simplicity of the interface design. Pressure programming during the chromatographic separation also allows precise control over the solvating power of the supercritical fluid mobile phase. The direct fluid injection interface provides for transfer of the total SFC effluent into a chemical ionization source. Results are presented to illustrate the separation analysis of mixtures of aromatic hydrocarbons and styrene oligomers using n-pentane and carbon dioxide as the mobile phase.

• Research Organization: Pacific Northwest Lab., Richland, WA (USA); Brigham Young Univ., Provo, UT (USA). Dept. of Chemistry
• DOE Contract Number: AC06-76RL01830
• OSTI ID: 7031650
• Report Number(s): PNL-SA-10074; CONF-820883-1; ON: DE83001951
• Country of Publication: United States
• Language: English

Related Subjects

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY
400104* -- Spectral Procedures-- (-1987)
AROMATICS
BLOOD VESSELS
BODY
CAPILLARIES
CARDIOVASCULAR SYSTEM
CHROMATOGRAPHY
DISPERSIONS
HYDROCARBONS
INTERFACES
MASS SPECTROSCOPY
MATERIALS
MIXTURES
ORGANIC COMPOUNDS
ORGANIC POLYMERS
ORGANS
PETROCHEMICALS
PETROLEUM PRODUCTS
PLASTICS
POLYCYCLIC AROMATIC HYDROCARBONS
POLYMERS
POLYOLEFINS
POLYSTYRENE
POLYVINYLS
SEPARATION PROCESSES
SPECTROSCOPY
SYNTHETIC MATERIALS