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Differentiation and radiosensitivity of hemopoietic stem cells of hypokinetic mice

Journal Article · · Radiobiology (USSR) (Engl. Transl.); (United States)
OSTI ID:5590834
It was established that there is a change in erythroid differentiation and CFU (colony-forming unit) radiosensitivity at the early stage of hypokinesia (3 days), when there is prevalence of the stress reaction. This effect is related to redistribution of T lymphocytes, the number of which increases in the bone marrow of hypokinetic mice. At the late stages of hypokinesia (30 days), when the changes in the body are attributable to hypokinesia, there is normalization of differentiation and radiosensitivity of CFU.
OSTI ID:
5590834
Journal Information:
Radiobiology (USSR) (Engl. Transl.); (United States), Journal Name: Radiobiology (USSR) (Engl. Transl.); (United States) Vol. 19:2; ISSN RADBA
Country of Publication:
United States
Language:
English

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Related Subjects

560152* -- Radiation Effects on Animals-- Animals
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMAL CELLS
ANIMALS
BIOLOGICAL EFFECTS
BIOLOGICAL MATERIALS
BIOLOGICAL RADIATION EFFECTS
BIOLOGICAL STRESS
BLOOD
BLOOD CELLS
BLOOD FORMATION
BODY
BODY FLUIDS
BONE MARROW
CELL DIFFERENTIATION
CFU
CONNECTIVE TISSUE CELLS
DATA
DATA FORMS
ELECTROMAGNETIC RADIATION
ERYTHROCYTES
EXPERIMENTAL DATA
GAMMA RADIATION
HEMATOPOIETIC SYSTEM
INFORMATION
IONIZING RADIATIONS
ISOLATED VALUES
LEUKOCYTES
LYMPHOCYTES
MAMMALS
MATERIALS
MICE
NUMERICAL DATA
ORGANS
RADIATION EFFECTS
RADIATIONS
RADIOSENSITIVITY
RADIOSENSITIVITY EFFECTS
RODENTS
SOMATIC CELLS
STEM CELLS
TISSUES
VERTEBRATES