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Fate of 7,12-dimethylbenz(a)anthracene in rainbow trout, Salmo gairdneri

Journal Article · · Bull. Environ. Contam. Toxicol.; (United States)
DOI:https://doi.org/10.1007/BF01691785· OSTI ID:5588641
; ;

Polycyclic aromatic hydrocarbons (PAH) are contaminants of surface waters and sediments, especially near urban centers. Although aquatic biota accumulate PAHs from environmental sources, metabolism may be rapid, and biota sampled from contaminated areas often have concentrations lower than might be estimated from bioconcentration factors. In some cases PAH metabolism by aquatic biota may create reactive intermediates, some of which have been related to chronic effects in fishes. This report describes the fate and distribution of 7,12-dimethylbenz(a)anthracene (DMBA) after oral administration to rainbows trout (Salmo gairdneri). Emphasis has been placed on the disposition of DMBA among tissues and on DMBA transformation in the hepatobiliary system.

Research Organization:
New York Univ. Medical Center, Tuxedo Park
OSTI ID:
5588641
Journal Information:
Bull. Environ. Contam. Toxicol.; (United States), Journal Name: Bull. Environ. Contam. Toxicol.; (United States) Vol. 39:1; ISSN BECTA
Country of Publication:
United States
Language:
English

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Related Subjects

550501 -- Metabolism-- Tracer Techniques
560300* -- Chemicals Metabolism & Toxicology
59 BASIC BIOLOGICAL SCIENCES
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMALS
AQUATIC ORGANISMS
AROMATICS
BODY
CARBON 14 COMPOUNDS
CONDENSED AROMATICS
DIGESTIVE SYSTEM
DIMETHYLBENZANTHRACENE
DISTRIBUTION
FISHES
GASTROINTESTINAL TRACT
GILLS
GLANDS
INTESTINES
KIDNEYS
LABELLED COMPOUNDS
LIVER
METABOLIC ACTIVATION
MUSCLES
ORGANIC COMPOUNDS
ORGANS
RESPIRATORY SYSTEM
RETENTION
STOMACH
TISSUE DISTRIBUTION
TROUT
VERTEBRATES