Periodic depuration of anthracene metabolites by rainbow trout

Journal Article · Sun Jul 01 04:00:00 EDT 1984 · Trans. Am. Fish. Soc.; (United States)

DOI:https://doi.org/10.1577/1548-8659(1984)113<513:PDOAMB>2.0.CO;2· OSTI ID:5001098

Linder, G; Bergman, H L

Rainbow trout Salmo gairdneri, statically exposed to 36 ..mu..g/liter anthracene (including 9-/sup 14/C-C anthracene), bioconcentrated the polynuclear aromatic hydrocarbon 200 times the exposure concentration over 18 hours. Then, during a 96-hour clearance periods, mass-balance analysis of fish and water samples indicated that anthracene was rapidly converted to polar metabolites(s), then eliminated periodically. Maximum depuration occurred during the dark phase of a 16-hour-light: 8-hour-dark photocycle. Of the 2-3% contribution of /sup 14/C metabolites(s) to the total /sup 14/C residue, nearly half came from the bile. This periodic depuration may be circadian, although this requires confirmation by further work; to the extent it affects metabolic fate of bioconcentrated organics, periodic depuration undoubtedly contributes to differences between predicted and observed bioconcentration factors.

• Research Organization: Univ. of Wyoming, Laramie
• OSTI ID: 5001098
• Journal Information: Trans. Am. Fish. Soc.; (United States), Journal Name: Trans. Am. Fish. Soc.; (United States) Vol. 113:4; ISSN TAFSA
• Country of Publication: United States
• Language: English

Related Subjects

550601 -- Medicine-- Unsealed Radionuclides in Diagnostics
560305* -- Chemicals Metabolism &amp; Toxicology-- Vertebrates-- (-1987)
62 RADIOLOGY AND NUCLEAR MEDICINE
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMALS
ANTHRACENE
AQUATIC ORGANISMS
AROMATICS
BIOLOGICAL ACCUMULATION
CARBON 14 COMPOUNDS
CLEARANCE
COMPARTMENTS
CONDENSED AROMATICS
DAILY VARIATIONS
EXCRETION
FISHES
HYDROCARBONS
LABELLED COMPOUNDS
METABOLITES
ORGANIC COMPOUNDS
PURIFICATION
TROUT
VARIATIONS
VERTEBRATES