Microwave effects on granulocyte and macrophage precursor cells of mice in vitro
Colony-forming unit cells from the femurs and tibias of 2-month-old C3H mice were exposed to 2450-MHz CW microwaves in a specially designed fluid-filled waveguide exposure system. The cells were suspended in glass micropipets and exposed to 30 to 1000 mW/cm/sup 2/ of incident power densities corresponding to specific absorption rates of 60 to 2000 mW/g for 15 min. There was no reduction in the number of colonies formed on days 6 and 12 at 30 mW/cm/sup 2/ (60 mW/g), but as the exposure was increased up to a level of 1000 mW/cm/sup 2/ (2000 mW/g) there was a corresponding reduction in the number of colonies formed by microwave-treated cells, compared to sham-exposed cells. Thus, there was a dose-dependent reduction in the number of colonies formed by microwave-exposed bone marrow cells when compared to their sham-exposed counterparts.
- Research Organization:
- Wayne State Univ., Detroit, MI
- OSTI ID:
- 5578072
- Journal Information:
- Radiat. Res.; (United States), Journal Name: Radiat. Res.; (United States) Vol. 80:2; ISSN RAREA
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
Cells
& Tissue Culture
560121 -- Radiation Effects on Cells-- External Source-- (-1987)
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMAL CELLS
ANIMALS
BIOLOGICAL EFFECTS
BIOLOGICAL MATERIALS
BIOLOGICAL RADIATION EFFECTS
BLOOD
BLOOD CELLS
BODY
BODY FLUIDS
CONNECTIVE TISSUE CELLS
ELECTROMAGNETIC RADIATION
IN VITRO
IRRADIATION
LEUKOCYTES
MACROPHAGES
MAMMALS
MATERIALS
MICE
MICROWAVE RADIATION
ORGANS
PHAGOCYTES
RADIATION EFFECTS
RADIATIONS
RODENTS
SKELETON
SOMATIC CELLS
VERTEBRATES