Hematologic effects in mice exposed to pulsed and cw microwaves. Annual report
Mice were exposed in the far field of an anechoic chamber to 2880-MHz pulsed microwaves (2.3-microsec pulses, 100/sec) 3-7.5 hr daily for 60-360 hr. In two of five studies with 5-mW/sq cm pulsed microwaves there was a significant increase in bone marrow cellularity compared to the sham-exposed groups, but in the other three exposures at 5-mW/sq cm no significant effect was observed. Significant differences were occasionally seen in erythrocyte, leukocyte and platelet measurements from microwave-exposed groups, but were not consistently observed. The only effect seen in mice exposed to 5-mW/sq cm CW microwaves was a reduction in reticulocyte concentrations (P less than 0.02). In one of four exposures at 10-mW/sq cm pulsed microwaves, mean bone marrow cellularity was reduced (P less than 0.02) in the microwave-exposed mice, and in another group the concentration of circulating lymphocytes was increased (P less than 0.05). In only one exposure (10-mW/sq cm for 360 hr) was any effect noted on serum proteins: a reduction (P less than 0.02) to 5.1 + or - 0.29 g/dl in the exposed vs 5.6 + or - 0.36 g/dl in the sham-exposed mice. This was due to a decrease in alpha and beta-globulins, with no effect on albumin or gamma-globulin concentrations. No effect on bone marrow hematopoietic colony-forming units (CFU) was revealed by CFU-agar assay techniques following exposure of mice to 5-mW/sq cm pulsed microwaves. In 1 of 4 exposures of mice to 10-mW/sq cm pulsed microwaves there was a significant (P less than 0.05) increase in CFU-agar colonies.
- Research Organization:
- Battelle Pacific Northwest Labs., Richland, WA (USA)
- OSTI ID:
- 5544078
- Report Number(s):
- AD-A-065326
- Country of Publication:
- United States
- Language:
- English
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59 BASIC BIOLOGICAL SCIENCES
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMALS
BIOLOGICAL EFFECTS
BIOLOGICAL MATERIALS
BLOOD
BLOOD CELLS
BODY
BODY FLUIDS
BONE MARROW
CFU
CHRONIC EXPOSURE
CHRONIC IRRADIATION
DISEASES
ELECTROMAGNETIC RADIATION
GLOBULINS
HEMATOPOIETIC SYSTEM
IRRADIATION
MAMMALS
MICE
MICROWAVE RADIATION
ORGANIC COMPOUNDS
ORGANS
PATHOLOGICAL CHANGES
PROTEINS
PULSED IRRADIATION
RADIATIONS
RODENTS
TISSUES
VERTEBRATES