Regional lung perfusion and ventilation with radioisotopes in cervical cord-injured patients

Journal Article · Thu May 01 04:00:00 EDT 1986 · Clin. Nucl. Med.; (United States)

DOI:https://doi.org/10.1097/00003072-198605000-00016· OSTI ID:5562122

Hiraizumi, Y; Fujimaki, E; Hishida, T; Maruyama, T; Takeuchi, M

In general, cervical cord-injured patients present with restrictive pulmonary dysfunction resulting from paralysis of the intercostal muscles. Vital capacity frequently decreases below 50% of that in normal subjects, and their respiratory pattern frequently includes paradoxical movement in which the intercostal spaces sink and the abdomen distends at inspiration. Ventilation scintigraphy using Xe-133 and pulmonary perfusion scintigraphy using Tc-99m macroaggregated albumin (MAA) were performed on nine cervical cord-injured patients and four normal subjects to investigate regional lung functions in the cervical cord-injured patients. Pulmonary perfusion scintigraphy, in which measurement was made in the supine position, revealed no differences between the patients and the normal subjects. The inhomogeneous ventilation/perfusion distribution was presumed to have resulted from change in regional intrapleural pressure due to paradoxical movement of the thoracic cage. Washing and washout times were prolonged by paralysis of the intercostal muscles. These phenomena were particularly apparent in the upper and middle lung regions where compensating action by movement of the diaphragm is small.

• Research Organization: Showa Univ., Tokyo, Japan
• OSTI ID: 5562122
• Journal Information: Clin. Nucl. Med.; (United States), Journal Name: Clin. Nucl. Med.; (United States) Vol. 5; ISSN CNMED
• Country of Publication: United States
• Language: English

Related Subjects

550601* -- Medicine-- Unsealed Radionuclides in Diagnostics
62 RADIOLOGY AND NUCLEAR MEDICINE
ALBUMINS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BODY
CENTRAL NERVOUS SYSTEM
COUNTING TECHNIQUES
DAYS LIVING RADIOISOTOPES
DIAGNOSTIC TECHNIQUES
DYNAMIC FUNCTION STUDIES
EVEN-ODD NUCLEI
HOURS LIVING RADIOISOTOPES
INJURIES
INTERMEDIATE MASS NUCLEI
INTERNAL CONVERSION RADIOISOTOPES
ISOMERIC NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
LUNGS
MUSCLES
NERVOUS SYSTEM
NUCLEI
ODD-EVEN NUCLEI
ORGANIC COMPOUNDS
ORGANS
PATIENTS
PERFUSED ORGANS
PROTEINS
RADIOISOTOPE SCANNING
RADIOISOTOPES
RESPIRATION
RESPIRATORY SYSTEM
SCINTISCANNING
SPINAL CORD
TECHNETIUM 99
TECHNETIUM ISOTOPES
XENON 133
XENON ISOTOPES
YEARS LIVING RADIOISOTOPES