Study of regional pulmonary functions in normal and diseased subjects by $sup 133$Xe scanning method

Journal Article · Thu Nov 01 04:00:00 EST 1973 · Tohoku Igaku Zasshi, v. 85, no. 6, pp. 296-314

OSTI ID:4327016

Takahashi, K

Pulmonary mechanics and regional pulmonary functions in normal and diseased subjects were analyzed by the newly provided /sup 133/Xe scanning device. In upright normal men, lung volume, ventilation, and perfusion were regionally affected by gravity as already reported by others. The perfusion/volume ratios were increased from the top to the base of the lung, however the ventilation/ volume ratios were kept constant through the lung. Intrathoracic pressure was related with diaphragmatic movement such that it often indicated very positive in the dependent regions at low lung volume in cases of large diaphragmatic movement. It was concluded that diaphragmatic movement was a very important factor determining the distribution of ventilation. The presented /sup 133/Xe scanning device was suggested quite useful in detection of regional distribution in function such as delays of gas clearance, residual volume/total lung capacity in emphysematous patients. Furthermore it was shown that the present scannlng method was also excellent in analysis of regional perfusion which was not shown by /sup 131/I-MAA scanning method in hilar lung cancer. (auth)

• Research Organization: Tohoku Univ., Sendai
• NSA Number: NSA-29-027169
• OSTI ID: 4327016
• Journal Information: Tohoku Igaku Zasshi, v. 85, no. 6, pp. 296-314, Journal Name: Tohoku Igaku Zasshi, v. 85, no. 6, pp. 296-314; ISSN THIZA
• Country of Publication: Japan
• Language: Japanese

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