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Comparison of /sup 133/Xe single-breath and washout imaging in the scintigraphic diagnosis of pulmonary embolism

Conference · · Radiology; (United States)
OSTI ID:6786276
To compare the utility of /sup 133/Xe single-breath (SB) and prolonged washout (WO) imaging in the scintigraphic diagnosis of pulmonary embolism, ventilation and perfusion studies of 66 patients who had pulmonary angiography within 48 hours were reviewed. The single-breath-perfusion (SB-P) and washout-perfusion (WO-P) studies agreed in 59 of 66 patients (89%). Each of the seven patients with disparate interpretations had an SB-P interpretation with a high probability for pulmonary embolism and a WO-P reading of low probability, with /sup 133/Xe retention in areas which appeared normal on the SB image. Single-breath images with /sup 133/Xe are not suitable as the sole determinant of ventilation-perfusion (V-P) match or mismatch, especially when subsegmental perfusion defects are present. Prolonged washout imaging improves the specificity of V-P imaging in patients with suspected pulmonary embolism.
Research Organization:
Johns Hopkins Medical Institutions, Baltimore, MD
OSTI ID:
6786276
Conference Information:
Journal Name: Radiology; (United States) Journal Volume: 137:2
Country of Publication:
United States
Language:
English